Time-to-peak values can estimate hepatic functional reserve in patients undergoing surgical resection: a comparison between perfusion CT and indocyanine green retention test.

J Comput Assist Tomogr

From the *Departments of Radiology and †Surgery, G.B. Rossi Hospital, University of Verona, Verona, Italy; and ‡Department of Prevention, Provincial Health Services Agency, Trento, Italy; Department of Public Health and Community Medicine, University of Verona, Italy.

Published: November 2014

AI Article Synopsis

  • The study aimed to assess the effectiveness of perfusion computed tomography (CT) in estimating liver function in patients before they undergo surgery for liver tumors, comparing it with the traditional indocyanine green retention test.
  • A total of 31 patients with liver cancer participated, undergoing both tests on the same day, and their results were analyzed statistically.
  • The findings showed a strong relationship between the results from perfusion CT and the indocyanine green test, suggesting that perfusion CT could serve as a valuable noninvasive alternative for evaluating liver function before surgery.*

Article Abstract

Objective: To evaluate the potential usefulness of perfusion computed tomography (CT) for the estimation of hepatic functional reserve in patients scheduled for surgical resection and to compare the results with those of the indocyanine green retention test results.

Methods: Thirty-one patients with hepatobiliary malignancies were included. Perfusion CT and indocyanine green retention test were performed on the same day, and their results were compared using Pearson correlation test.

Results: A strong correlation was found between perfusion CT time-to-peak values and indocyanine green retention rate at 15 minutes and indocyanine green plasma disappearance rate values (R, 0.789 and -0.790; R, 0.832 and -0.823, respectively; P < 0.0001).

Conclusions: Perfusion CT may be useful for the preoperative noninvasive estimation of hepatic functional reserve for patients undergoing liver resection.

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Source
http://dx.doi.org/10.1097/RCT.0000000000000102DOI Listing

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