Purpose: To investigate the prevalence of Toxoplasma gondii and Toxocara canis in patients with uveitis.
Method: Patients with uveitis were examined. Serum antibodies to T. gondii and T. canis were tested by using enzyme-linked immunosorbent assay (ELISA). Polymerase chain reaction (PCR) was done using blood and aqueous humor (AH).
Results: 98 patients were enrolled. Mean age was 43.5 ± 13.2 years. Six patients were seropositive for T. gondii with the following pattern-anterior uveitis: 1; posterior uveitis with retinitis: 2; pan uveitis: 2. One patient had a positive result of PCR for T.gondii in AH, who showed pan uveitis. 23 patients were positive to serum IgG for T. canis with the following clinical manifestation-granuloma: 6; pigmented scar: 3; virtrits: 6-but none were PCR positive.
Conclusion: T.gondii and T.canis are still one of the important causes of uveitis. Ocular toxocariasis is not an uncommon cause of uveitis even in adult.
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http://dx.doi.org/10.3109/09273948.2013.841491 | DOI Listing |
Int J Biol Macromol
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National Animal Protozoa Laboratory and School of Veterinary Medicine, China Agricultural University, Beijing 100193, China; Shenzhen Key Laboratory of Pathogenic Microbes and Biosafety, and Laboratory of Zoonotic Diseases, School of Public Health (Shenzhen), Sun Yat-Sen University, Shenzhen Campus, Shenzhen 518107, China. Electronic address:
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Department of Health Biohazards and Parasitology, Institute of Rural Health, Jaczewskiego 2, 20-090 Lublin, Poland.
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Department of Biological and Environmental Sciences, Le Moyne College, Syracuse, NY 13214, USA.
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Department of Veterinary Pathobiology, Oklahoma State University, Stillwater, OK 74078, USA.
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Institute of Zoology, Bahauddin Zakariya University, Multan 60800, Pakistan. Electronic address:
Ticks are the second most important hematophagous ectoparasites after mosquitoes and serve as vectors for various pathogens, transmitting them to wild and domestic animals, as well as humans. Argas persicus are the soft ticks that are known to parasitize domestic poultry. Hard ticks are known to be the reservoir of Toxoplasma (T.
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