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Developing normalized strength scores for neuromuscular research.
Muscle Nerve
February 2013
Neurology Clinical Trials Unit, Massachusetts General Hospital, 149 13th Street, Room 2274, Charlestown, Massachusetts 02129, USA.
Introduction: The Accurate Test of Limb Isometric Strength (ATLIS) device can reliably measure the strength of 12 muscle groups using a fixed load cell. The purpose of this study was to analyze ATLIS data from healthy adults to calculate an individual's predicted strength scores.
Methods: ATLIS data were collected from 432 healthy adults.
Validation of a new strength measurement device for amyotrophic lateral sclerosis clinical trials.
Muscle Nerve
January 2012
Neurology Clinical Trials Unit, Massachusetts General Hospital, 149 13th Street, Room 2274, Charlestown, Massachusetts 02129, USA.
Introduction: Strength measures with reduced variability and higher sensitivity could improve efficiency in clinical trials of amyotrophic lateral sclerosis (ALS). The Accurate Test of Limb Isometric Strength (ATLIS) was developed to precisely and conveniently measure force in 12 muscle groups. In this study we evaluate the reliability and validity of the ATLIS testing protocol.
View Article and Find Full Text PDFNeurology education in Latin America and the World Federation of Neurology.
J Neurol Sci
November 2010
The World Federation of Neurology (WFN) is the international body representing the specialty of neurology in more than 100 countries/regions of the globe. The WFN was organized as a federation of national neurologic societies in 1957. A primary goal of the WFN is to assist low-resource countries in providing meaningful education for its neurologic health care providers and thus improve the neurologic health of its citizens.
View Article and Find Full Text PDFDeveloping a neurology training program in Honduras: a joint project of neurologists in Honduras and the World Federation of Neurology.
J Neurol Sci
February 2007
Education Committee, World Federation of Neurology, Honduras.
One of the major barriers to the provision of quality care for patients with neurological disorders in developing countries is a low ratio of neurologists per inhabitants, the World Health Organization recommends one neurologist per 100,000. In 1998 Honduras had one neurologist per 325,000 inhabitants and all the neurologists were trained outside the country. The Education Committee of the World Federation of Neurology (WFN), in collaboration with the Postgraduate Direction of the National Autonomous University of Honduras, the Honduran Neurological Association, and the Honduran Secretary of Health helped establish the country's first Neurology Training Program in 1998.
View Article and Find Full Text PDFPromoting excellence in end-of-life care in ALS.
Amyotroph Lateral Scler Other Motor Neuron Disord
September 2005
The Elenor & Lou Gehrig MDA/ALS Research Center, Columbia University Neurological Institute, New York, NY 10032, USA.
The type and quality of end-of-life care varies greatly in ALS; the time to initiate end-of-life care is not defined, and decision making is hampered by logistical and financial barriers. There has been no systematic review of these issues in ALS. The goals of this initiative are to: 1) improve end-of-life care for patients with ALS and families based on what limited evidence is available; 2) increase awareness, interest, and debate on the end-of-life care in ALS; and 3) identify areas needed for new prospective clinical research.
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