Extremes of age are associated with indeterminate QuantiFERON-TB gold assay results.

J Clin Microbiol

Academic Unit of Clinical & Experimental Sciences, Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, United Kingdom Department of Paediatric Infectious Diseases & Immunology, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom Southampton NIHR Respiratory Biomedical Research Unit, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom NIHR Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom.

Published: July 2014

Results from 3,263 QuantiFERON-TB Gold in-tube (QFT-GIT) assays were analyzed to determine the impact of age on test performance. The proportion of indeterminate results was significantly higher in pediatric and elderly (9.1% and 7.4%, respectively) than in adult (2.6%; chi-square test, P < 0.0001) patients. A detailed analysis of indeterminate QFT-GIT assay results is presented.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097686PMC
http://dx.doi.org/10.1128/JCM.00814-14DOI Listing

Publication Analysis

Top Keywords

quantiferon-tb gold
8
extremes age
4
age associated
4
associated indeterminate
4
indeterminate quantiferon-tb
4
gold assay
4
assay 3263
4
3263 quantiferon-tb
4
gold in-tube
4
in-tube qft-git
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!