A comparison between the BD MAX MRSA and Xpert MRSA assays was performed using 239 nares samples. A 97.9% overall agreement between the two molecular assays was observed. The BD MAX MRSA assay proved to be a reliable alternative for a highly automated system to detect methicillin-resistant Staphylococcus aureus (MRSA) in patient nares samples.
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http://dx.doi.org/10.1128/JCM.00237-14 | DOI Listing |
ACS Appl Bio Mater
January 2025
Department of Chemistry, North Carolina State University, Raleigh, North Carolina 27695, United States.
Ligand-functionalized InP-based quantum dots (QDs) have been developed as an innovative class of nontoxic photosensitizer suitable for antimicrobial applications, aimed at reducing or preventing pathogen transmission from one host to another via high contact surfaces. A hot injection method followed by functionalization via ligand exchange with 9-anthracene carboxylic acid (ACA) yielded the desired core/shell InP/ZnSe/ZnS QDs. Transmission electron microscopy (TEM) revealed these QDs to be uniform in size (∼3.
View Article and Find Full Text PDFAccess Microbiol
November 2024
Department of Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada.
Our study aimed to identify the bacterial source of a previously detected mobile antibiotic-resistant gene, , found in a lake that serves as a source to a water treatment plant operated by a First Nation reserve. Three methicillin-resistant presumptive spp. isolated from the sample using selective media were verified as positive by PCR.
View Article and Find Full Text PDFBMC Infect Dis
November 2024
Infection Prevention and Control Unit, Rambam Health Care Campus, P.O. Box 9602, Haifa, 31096, Israel.
Background: While effective preventive measures reduce hospital-acquired infections (HAIs) and the spread of multi-drug resistant organisms (MDROs), studies on the impact of the COVID-19 pandemic and its associated preventive measures remain inconclusive.
Objective: To assess the impact of COVID-19 on HAIs and MDROs and to compare it with the effect of seasonal influenza.
Methods: A retrospective cohort study analyzed prospectively collected data from a tertiary hospital in Haifa, northern Israel, from 2016 to 2021.
Cell Rep
November 2024
Department of Cellular Microbiology, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117 Berlin, Germany. Electronic address:
The antimicrobial activity of histones was discovered in the 1940s, but their mechanism of action is not fully known. Here we show that methicillin-resistant Staphylococcus aureus (MRSA) is susceptible to histone H1 (H1), even in the presence of divalent cations and serum. Through selective evolution and a genome-wide screen of a transposon library, as well as physiological and pharmacological experiments, we elucidated how H1 kills MRSA.
View Article and Find Full Text PDFRSC Adv
October 2024
Chemistry Department, Faculty of Science, Beni-Suef University Beni-Suef 62511 Egypt
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