AI Article Synopsis
- Prosthetic joint infection (PJI) is a serious complication that can occur after joint replacement surgeries, with key risk factors including prior surgeries and health conditions.
- Most PJIs are caused by bacteria like Staphylococcus aureus, which can form biofilms that complicate treatment.
- Diagnosis involves signs of infection and sometimes imaging, while prevention focuses on patient health and timely antibiotic use; treatment often requires removing implants and administering IV antibiotics.
Article Abstract
Prosthetic joint infection (PJI) is a serious and potentially devastating complication of arthroplasty. Prior arthroplasty, immunosuppression, severe comorbid conditions, and prolonged surgical duration are important risk factors for PJI. More than half of the cases of PJI are caused by Staphylococcus aureus and coagulase-negative staphylococci. The biofilm plays a central role in its pathogenesis. The diagnosis of PJI requires the presence of purulence, sinus tract, evidence of inflammation on histopathology, or positive microbiologic cultures. The use of diagnostic imaging techniques is generally limited but may be helpful in selected cases. The most effective way to prevent PJI is to optimize the health of patients, using antibiotic prophylaxis in a proper and timely fashion. Management of PJI frequently requires removal of all hardware and administration of intravenous antibiotics. This review summarizes and analyzes the results of previous reports of PJI and assesses the prevention and management of this important entity.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161774 | PMC |
| http://dx.doi.org/10.5301/jabfm.5000202 | DOI Listing |
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