When pulling a particle in a driven granular fluid with constant force Fex, the probe particle approaches a steady-state average velocity v. This velocity and the corresponding friction coefficient of the probe ζ=Fex/v are obtained within a schematic model of mode-coupling theory and compared to results from event-driven simulations. For small and moderate drag forces, the model describes the simulation results successfully for both the linear as well as the nonlinear region: The linear response regime (constant friction) for small drag forces is followed by shear thinning (decreasing friction) for moderate forces. For large forces, the model demonstrates a subsequent increasing friction in qualitative agreement with the data. The square-root increase of the friction with force found in [Fiege et al., Granul. Matter 14, 247 (2012)] is explained by a simple kinetic theory.
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Sci Rep
January 2025
Departamento de Ciencias de la Construcción, Facultad de Ciencias de la Construcción Ordenamiento Territorial, Universidad Tecnológica Metropolitana, Santiago, Chile.
There is an initiative driven by the carbon-neutrality nature of biochar in recent times, where various countries across Europe and North America have introduced perks to encourage the production of biochar for construction purposes. This objective aligns with the zero greenhouse emission targets set by COP27 for 2050. This research work seeks to assess the effectiveness of biochar in soils with varying grain size distributions in enhancing the soil-water characteristic curve (SWCC).
View Article and Find Full Text PDFNat Commun
December 2024
Department of Medicine, Columbia Center for Human Development and Stem Cell Therapies, Columbia University Irving Medical Center, New York, NY, USA.
Pluripotent stem cells possess a unique nuclear architecture characterized by a larger nucleus and more open chromatin, which underpins their ability to self-renew and differentiate. Here, we show that the nucleolus-specific RNA helicase DDX18 is essential for maintaining the pluripotency of human embryonic stem cells. Using techniques such as Hi-C, DNA/RNA-FISH, and biomolecular condensate analysis, we demonstrate that DDX18 regulates nucleolus phase separation and nuclear organization by interacting with NPM1 in the granular nucleolar component, driven by specific nucleolar RNAs.
View Article and Find Full Text PDFEur J Health Econ
December 2024
Reinier de Graaf Gasthuis, Delft, The Netherlands.
Background: Health economic evaluations require cost data as a key input, and reimbursement policies and systems should incentivize valuable care. Subfertility is a growing global phenomenon, and Dutch per-treatment DRGs alone do not support value-based decision-making because they don't reflect patient-level variation or the impact of technologies on costs across entire patient pathways.
Methods: We present a real-world micro-costing analysis of subfertility patient pathways (n = 4.
Data Brief
December 2024
School of Computing, Dublin City University, Dublin, Ireland.
Research in field sports often measures the performance of players during competitive games with individual and time-based descriptive statistics. Data is generated using GPS technologies, capturing simple data such as time (seconds) and position (latitude and longitude). While the data capture is highly granular and in relatively high volumes, the raw data are unsuited to any form of analysis or machine learning functions.
View Article and Find Full Text PDFPLoS Comput Biol
December 2024
Institute of Software Technology, Department of High-Performance Computing, German Aerospace Center, Cologne, Germany.
In the realm of infectious disease control, accurate modeling of the transmission dynamics is pivotal. As human mobility and commuting patterns are key components of communicable disease spread, we introduce a novel travel time aware metapopulation model. Our model aims to enhance estimations of disease transmission.
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