Introduction: The aim of the treatment of displaced scaphoid non-unions is the restoration of normal scaphoid anatomy. Restoration of normal scaphoid anatomy at an earlier stage might have functional benefits as maladaptive carpal ligament contractures and the development of preliminary osteoarthritis could be avoided. The purpose of this retrospective study was to determine if late reconstruction (delayed reconstruction group) was as effective as early reconstruction (early reconstruction group) of scaphoid non-union in restoring clinical and radiological outcome.
Patients And Methods: The early reconstruction group included patients who underwent surgery between 6 and 12 months after the original fracture. This group consisted of 14 male and 2 female patients. The delayed reconstruction group included patients who underwent surgery 12 or more months after the original fracture. This group consisted of 9 male and 1 female patients. Average time from injury to surgery in the early reconstruction group was 10 months (range 6-12 months) and mean postoperative follow-up period averaged 58 months (range 19-72 months). Average time from injury to surgery in the delayed reconstruction group was 69 months (range 12-88 months) and mean postoperative follow-up period averaged 62 months (range 24-80 months). All patients showed a humpback deformity as well as a DISI deformity with the radiolunate angle being greater than 15°. The outcome was assessed on the basis of measurement of active wrist range of motion and grip power. Wrist pain was evaluated using a visual analogue scale. Functional subjective outcome was evaluated with the DASH and PRWE scores. Results were compared to preoperative measurements as well as to the uninjured contralateral side. Pre- and post-operative radiographs were assessed for scapholunate angle (SLA) as a measure of palmar rotation and radiolunate angle (RLA). The presence of DISI was defined by a difference of >60° for the SLA or of >10° for the RLA between the affected and unaffected wrist.
Results: In the early reconstruction group bone union and correction of DISI deformity could be achieved for all patients (n = 16). In the delayed reconstruction group bone union could only be achieved without correction of the DISI deformity in six patients (60 %). In four patients (40 %) of the delayed reconstruction group non-union persisted. For the early reconstruction group at final follow-up mean flexion-extension arc, mean ulnar-radial-deviation arc and mean grip strength were 82, 91.5 and 82 % of uninjured side, respectively. Mean pain level decreased from 6 points before surgery to 1 point at final follow-up. The preoperative DASH changed from 48 to 17 and the preoperative PRWE changed from 30 to 14. The SLA changed from 51° to 48° and the RLA from 18° to 9°. Six patients from delayed reconstruction group showed bone union, but no correction of DISI deformity at final follow-up. Functional and radiological results showed only slight improvement. The remaining four patients from delayed reconstruction group with a persistent non-union continued to experience pain, reduced grip strength and limited range of wrist movement and DISI deformity persisted.
Conclusion: In conclusion, wedge-shaped bone grafting of scaphoid non-union leads to increased functional scores as well as to improved carpal angles as long as bony union can be achieved. Remaining non-union and the inability to correct DISI deformity are severely correlated with an increased time frame between fracture and surgical treatment. Furthermore, the vascularization of the proximal fragment and patients' smoking habits has to be taken into consideration preoperatively.
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http://dx.doi.org/10.1007/s00402-014-2007-7 | DOI Listing |
Int Urogynecol J
January 2025
Department of Urogynecology and Reconstructive Pelvic Surgery, Atlantic Health System, 435 South Street, Suite 370, Morristown, NJ, 07960, USA.
Introduction And Hypothesis: The objective of our study was to evaluate the need for antibiotic prophylaxis for urinary tract infection (UTI) prevention before Onabotulinum toxin A injection for overactive bladder (OAB). We hypothesize that the lack of antibiotic prophylaxis might not be inferior to administering prophylaxis.
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Facial Plast Surg Aesthet Med
January 2025
Division of Facial Plastic and Reconstructive Surgery, Stanford University School of Medicine, Stanford, California, USA.
To investigate the effectiveness of isotretinoin use in patients with thick nasal skin to improve rhinoplasty outcomes. The Population Intervention Comparison Outcome framework was utilized for selecting relevant studies for review. The databases of Medline, Embase, Cinahl, Central, Scopus, and Web of Science were searched in June 2024.
View Article and Find Full Text PDFJ Biomed Mater Res A
January 2025
Department of Orthopedics, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Bone defects are difficult to treat clinically and most often require bone grafting for repair. However, the source of autograft bone is limited, and allograft bone carries the risk of disease transmission and immune rejection. As tissue engineering technology advances, bone replacement materials are playing an increasingly important role in the treatment of bone defects.
View Article and Find Full Text PDFJ Vet Dent
January 2025
Department of Dentistry, Oral and Maxillo-facial Surgery, Eastcott Veterinary Referrals, Part of Linnaeus Group, Swindon, UK.
Canine acanthomatous ameloblastoma (CAA) is an invasive benign epithelial odontogenic tumour most commonly affecting the mandible of large breed dogs. To the author's knowledge, this report describes the first computer-aided design patient-specific implant (PSI) that has been placed for a critical sized bone defect in mandibular reconstruction of a dog in the UK. The aim was to restore mandibular stability using a regenerative approach combining a titanium locking plate and compression-resistant matrix infused with recombinant human bone morphogenetic protein-2 (rhBMP-2) to bridge the 85 mm mandibular defect created by a segmental mandibulectomy.
View Article and Find Full Text PDFInt J Cardiol Heart Vasc
February 2025
The Azrieli Faculty of Medicine in the Galilee, Bar-Ilan University, Zefat, Israel.
Introduction: Cardiac computerized tomographic angiography (CCTA) is perceived as a non-invasive tool for assessment of coronary vessel anatomy. Feature tracking echocardiography has recently emerged as a tool for assessment of regional and global left ventricular function. We aimed to explore the applicability of echocardiographic strain on CCTA cine clips and assess whether global and regional strain parameters are associated with the extent of coronary stenosis.
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