Perineural fibrosis and scarring of superficial nerves can occu r secondary to chronic frictional forces. This results in a tender lump in the nerve and hyperesthesia of the area of its distribution. Bowler's thumb is a well known entity which involves the ulna side digital nerve of the thumb at the level of the MP joint. This article describes a perineural fibrosis of the digital branch of the thumb in a jeweller who presented with pain and swelling at the center interphalangeal joint. Surgical excision of the fibrous mass and neurolysis has relieved the symptoms.
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http://dx.doi.org/10.3928/0147-7447-19830401-05 | DOI Listing |
Purpose: The interdigital nerve neuroma of the forefoot is commonly known as Morton's Neuroma. Many authors have described and treated this condition before and after Morton. This study aims to investigate the past scientific literature to better understand what comprehension and treatments have been used to master this pathology.
View Article and Find Full Text PDFCurr Sports Med Rep
September 2024
Department of Radiology, Mayo Clinic, Rochester, MN.
Curr Cancer Drug Targets
September 2024
Department of Clinical Laboratory, Zhejiang Provincial Hospital of TCM, Hangzhou, Zhejiang 310006, P.R. China.
Pancreatic cancer is a highly malignant form of cancer that distinguishes itself from other gastrointestinal tumors through significant fibrosis and unique perineural invasion. These characteristics underscore the complexity of neural regulation within the pancreatic cancer Tumor Microenvironment (TME). This review aimed to explore the regulatory mechanisms and crosstalk among stromal cells and their factors within the pancreatic cancer microenvironment.
View Article and Find Full Text PDFReg Anesth Pain Med
July 2024
Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, Korea (the Republic of)
Background: Dexamethasone palmitate (DEP), a prodrug of dexamethasone (DEX), is a synthetic corticosteroid medication distinguished by the inclusion of a fatty acid component known as palmitate. This study introduces DEP as a novel therapeutic option for spinal epidural injection, aiming to provide safer and longer-lasting pain relief as an alternative to for patients with spinal stenosis.
Methods: 40 rats were randomly divided into four groups: those receiving epidural administration of normal saline (NS), and DEP in the lumbar spinal stenosis (LSS) model, and non-model rats receiving epidural NS administration.
Ann Surg Oncol
November 2024
Department of Surgery, Regional Academic Cancer Center Utrecht, Utrecht University, University Medical Center Utrecht Cancer Center & St. Antonius Hospital Nieuwegein, Utrecht, The Netherlands.
Background: Distinguishing postoperative fibrosis from isolated local recurrence (ILR) after resection of pancreatic ductal adenocarcinoma (PDAC) is challenging. A prognostic model that helps to identify patients at risk of ILR can assist clinicians when evaluating patients' postoperative imaging. This nationwide study aimed to develop a clinically applicable prognostic model for ILR after PDAC resection.
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