An adult patient with ocular myasthenia and unusually long spontaneous remission.

Case Rep Neurol Med

Department of Neurology, Ibn Sina Hospital, P.O. Box 25427, 13115 Safat, Kuwait.

Published: May 2014

AI Article Synopsis

  • A 33-year-old male developed ocular myasthenia gravis (MG) but tested negative for anti-acetylcholine receptor antibodies.
  • After treatment with a cholinesterase blocker for 5 months, he achieved complete remission for 17 years without treatment.
  • Recently, he relapsed with ocular symptoms, tested positive for antibodies, showed abnormal results in a facial muscle test, and is now managed with steroids.

Article Abstract

A male patient developed ocular myasthenia gravis (MG) at the age of 33. He was anti-acetylcholine receptor antibody (anti-AChR Ab) negative. He received cholinesterase blocker for 5 months and went into a complete clinical remission that lasted untreated for 17 years. He relapsed recently with ocular symptoms only. He is now anti-AChR Ab positive and SFEMG is abnormal in a facial muscle. The patient is controlled with steroids. He had one of the longest spontaneous remissions reported in the natural history of MG, particularly unusual for an adult with the disease.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005048PMC
http://dx.doi.org/10.1155/2014/372769DOI Listing

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