To protect pedestrians, many countries give them priority at uncontrolled mid-block crosswalks or pedestrian crossings. However, the actual driver yielding rate is not always satisfactory (only 3.5% in this study). To increase the yielding rate, this study proposed eleven pedestrian gestures to inform drivers of their intent to cross. The gestures were evaluated based on the process of human interaction with environment. Four gestures were selected as candidates to test in field experiments based on scores for visibility, clarity, familiarity and courtesy (see illustration in Fig. 2): (1) right elbow bent with hands erect and palm facing left (R-bent-erect), (2) left elbow bent with hands level and palm facing left (L-bent-level), (3) left arm extended straight to left side with palm erect facing left (L-straight-erect), and (4) a 'T' gesture for "Time-out". In the experiment, confederate pedestrians waiting at the roadside displayed the gestures (baseline: no gesture) to 420 vehicles at 5 sites in Beijing, China. When pedestrians used the L-bent-level gesture, the vehicle yielding rate more than tripled of that in the baseline condition. The L-bent-level gesture also resulted in a significant decrease in driving with unchanged speed (63.5-38.8%) and had no significant side effects in terms of drivers' horn use or lane changing. The effects of such gestures in other contexts such as when pedestrians are in the crosswalk and when they are interacting with turning vehicles are discussed, together with the applications in training vulnerable pedestrian groups (children or elderly) and facilitating pedestrian detection by drivers.
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http://dx.doi.org/10.1016/j.aap.2013.12.015 | DOI Listing |
Am J Sports Med
January 2025
Gelenkpunkt-Sports and Joint Surgery FIFA Medical Centre of Excellence, Innsbruck, Austria.
Background: Anterolateral ligament reconstruction (ALLR) or lateral extra-articular tenodesis (LET) has been used more frequently in conjunction with anterior cruciate ligament reconstruction (ACLR) in recent years. However, there are still concerns that these procedures may lead to complications such as overconstraint of the lateral compartment, stiffness, infections, tunnel convergence, and other intra- and postoperative complications because of increased surgical time and the need for additional procedures.
Hypothesis/purpose: The lateral extra-articular procedure will reduce the failure rate of reconstructed ACLs without increasing the number of complications.
J Immunoassay Immunochem
January 2025
Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Background: Application of antibodies in therapeutics and diagnostics are growing Continually. Herein, we aimed to find the most qualified immunoglobulin (Ig) chemical preparation method.
Methods: A rabbit was immunized against recombinant SARS-CoV-2 nucleocapsid (NP) and reactive polyclonal antibodies were prepared using the ammonium sulfate (AS), caprylic acid (CA), polyethylene glycol (PEG), and caprylic acid/ammonium sulfate (CA/AS) methods.
Clin Lymphoma Myeloma Leuk
December 2024
Section of Benign Hematology, Department of Internal Medicine, MD Anderson Cancer Center, Houston, TX. Electronic address:
Background: 'Standard of care' therapies for adult acute myeloid leukemia (AML) have yielded 5-year overall survival (OS) rates of 30%-45 %. Risk stratification and novel targeted therapies have improved 5-year OS rates to >75 % for certain groups in specialized centers.
Patients And Methods: This is a retrospective cohort analysis of outcomes in patients ≥18 years with newly diagnosed AML treated between 2005 and 2019 in the Harris Health County, Safety-Net Hospital System in Houston, TX.
Plant Sci
January 2025
Department of Cell & Molecular Biology, Faculty of Life Sciences & Biotechnology, Shahid Beheshti University, Tehran, Iran.
Rice yield strongly depends on panicle size and architecture but the genetics underlying these traits and their coordination with environmental cues through various signaling pathways have remained elusive. A genome-wide association study (GWAS) was performed to pinpoint the underlying genetic determinants for rice panicle architecture by analyzing 20 panicle-related traits using a data set consisting of 44,100 SNPs. We defined QTL windows around significant SNPs by the rate of LD decay for each chromosome and used these windows to identify putative candidate genes associated with the trait.
View Article and Find Full Text PDFUrology
January 2025
Department of Urology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
Objective: To evaluate the efficacy, recurrence rates, and safety profile of intravesical gemcitabine plus docetaxel versus standard Bacillus Calmette-Guérin (BCG) therapy for treating naïve non-muscle-invasive bladder cancer (NMIBC), focusing on reducing recurrence and progression concerns associated with transurethral resection (TURBT).
Methods: Relevant articles were identified and appraised through a structured assessment of the literature. Databases searched included PubMed, Medline, Scopus, and Science Direct.
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