[Mics of the Clostridium thermocellum in lignocellulose degradation--a review].

Clostridium thermocellum ( C. thermocellum ) is the dominant microorganism that can efficiently degrade lignocellulose. Extensive studies were done for secreting the cell surface-bound protein complex known as the cellulosome. C. thermocellum is regulated by carbon sources, reflected in overall multiple cellulase production and in the cellulosomal subunit profile. To produce a cellulosomal protein complex is a dynamic assembly process. In recent years, it becomes a hotspot to study how C. thermocellum senses the insoluble substrate, regulates the secretion of relevant enzymes, and assembles the supramolecular-degradation enzyme complex. This review summarized the research advance in genomics, transcriptomics, proteomics and extracellular carbohydrate-sensing mechanism in C. thermocellum, and analyzed the mechanism and dynamic process of C. thermocellum in lignocellulose degradation.