AI Article Synopsis
- - This study explored the feasibility of participants collecting nasal swabs at home to detect Staphylococcus aureus in a population-based research project conducted in Braunschweig, Germany.
- - Among 2,026 randomly selected residents, various interventions were tested to boost participation: cash incentives, lottery entries, reminders by mail, and a control group with no incentives.
- - Results showed the cash incentive led to the highest participation (24%), while compliance in returning the swabs was consistently high across the board (around 90%), indicating that this method is practical and could benefit large-scale microbiological studies.
Article Abstract
Objectives: Participant-collected serial nasal swabs would be a cost-efficient feature of prospective population-based microbiological studies. We examined the feasibility of serial anterior nasal self-swabbing for Staphylococcus aureus detection in a prospective population-based study in Braunschweig, Germany, and assessed the impact of three interventions on participation and compliance.
Methods: Two thousand twenty-six inhabitants were selected randomly from the resident registries and asked to self-collect a nasal swab monthly from July 2012 to January 2013 and return it by mail. The swabs were tested for the presence of S. aureus. Participation and compliance were assessed in four study groups (incremental cash incentive, participation in a lottery, reminder by mail, and control group without incentive or reminder).
Results: Baseline participation was highest in the cash incentive group (24%; 123/504) and lowest in the reminder group (16%; 83/509). Approximately 90% of the participants in all groups returned the swabs each month, demonstrating high compliance irrespective of the intervention. Laboratory analyses showed that most swabs were usable for bacteriological studies. S. aureus was detected at the expected frequency of 20-27%.
Conclusions: Home-based serial nasal self-swabbing proved to be feasible and highly acceptable and promises to be a cost-efficient tool for large-scale prospective population-based studies on bacterial infection or colonization.
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| http://dx.doi.org/10.1016/j.ijid.2014.01.021 | DOI Listing |
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