Biomedical applications of ovarian transvaginal ultrasonography in cattle.

Anim Biotechnol

a Centre for Biological Sciences , University of Southampton, Southampton General Hospital, Southampton , United Kingdom.

Published: December 2014

AI Article Synopsis

  • Ovarian transvaginal ultrasonography (OTU) is widely utilized in elite herds for commercial ovum pick-up programs, aiding in the study of factors affecting bovine oocyte development.
  • OTU allows for noninvasive sampling and treatment of ovarian structures, showing potential for in vivo gene therapy by delivering transgenes directly into the ovary.
  • The review discusses current OTU models and explores future applications in reproductive research, particularly focusing on in vivo gene transfer strategies for biomedical purposes.

Article Abstract

Ovarian transvaginal ultrasonography (OTU) has been used world-wide for commercial ovum pick-up programs for in vitro embryo production in elite herds, providing an excellent model for the elucidation of factors controlling bovine oocyte developmental competence. Noninvasive sampling and treatment of ovarian structures is easily accomplished with bovine OTU techniques providing a promising system for in vivo delivery of transgenes directly into the ovary. The current review summarizes existing bovine OTU models and provides prospective applications of bovine OTU to undertake research in reproductive topics of biomedical relevance, with special emphasis on the development of in vivo gene transfer strategies.

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Source
http://dx.doi.org/10.1080/10495398.2013.870075DOI Listing

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