AI Article Synopsis

  • The study observes unique oculomotor issues in a patient with an isolated right cerebellar tonsil infarction, revealing almost no smooth pursuit on the affected side and impaired pursuit on the opposite side.
  • The patient exhibited a subtle right-beating nystagmus without fixation and difficulties in gaze-holding, but showed a normal vestibulo-ocular reflex.
  • These results provide clearer diagnostic insights for cerebellar conditions, address ongoing debates from monkey studies, and enhance understanding of similarities between monkey and human cerebellar function.

Article Abstract

The oculomotor abnormalities with isolated infarction of the cerebellar tonsil are unknown. In a patient with acute infarction of the right tonsil, we found (1) nearly completely abolished ipsilateral smooth pursuit and impaired contralateral pursuit, (2) a low-amplitude ipsilesional right-beating nystagmus without fixation, (3) gaze-holding deficits, and (4) normal vestibulo-ocular reflex. These findings contrast with striking vestibular abnormalities reported with unilateral flocculus and anterior tonsil infarction. Taken together, these findings allow more diagnostic certainty in cerebellar patients, help resolve controversies about interpretation of experimental findings in monkeys, and clarify homologies between the monkey and human cerebellum.

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Source
http://dx.doi.org/10.1002/ana.24094DOI Listing

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