The immunofluorescence techniques with monospecific antibodies to lactoferrin (LF) and leukocytic thermostable alpha-glycoprotein (LT alpha-G) has demonstrated that both the proteins are specific components of the peripheral blood granulocytes of normal subjects. LF and LT alpha-G are detectable in the cytoplasmic granules of polynuclear leukocytes but not on the external surface of these cells' membranes. Differences between the direct and indirect immunofluorescence techniques, used for the detection of the granulocytic LF and LT alpha-G are discussed. Examinations of the blood smears from patients, operated on under artificial circulation, have shown that the emergence of granulocytic protein aggregates between the cells and LF and LT alpha-G sorption on the red cell surface indicate a disease.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Concentrations of lactoferrin (LF), alpha-microglobulin of fertility (AMGF) and specific thermostable alpha-glycoprotein (STAG) which are markers of the prostate, seminal vesicles and testiculi in ejaculate, respectively, were determined by Ouchterlony's immunodiffusion method in 148 patients with chronic prostatitis (group 1), 26 patients with combination of prostatitis with chronic epididymitis (group 2) and 22 healthy controls (group 3). After that the patients were given prostatilen. It was found that high pretreatment values of LF registered in groups 1 and 2 lowered close to those in the controls.
View Article and Find Full Text PDFThe authors studied concentrations of granulocytic proteins, lactoferrin, leukocytic thermostable alpha-glycoprotein in the blood plasma of patients with rheumatoid arthritis. High concentrations of the above proteins were observed in RA patients.
View Article and Find Full Text PDFThe authors studied the dynamics of C4-component of complement (C4), lactoferrin (LF), leukocytic thermostable alpha-glycoprotein (LT alpha G) in the blood serum of 54 patients with rheumatoid arthritis, 32 patients with systemic lupus erythematosus, 8 patients with systemic vasculitis under the effect of hemosorption (HS), enterosorption (ES) and also immunosuppressants (IS). In severe forms of systemic rheumatic diseases the blood serum exhibits a decreased content of C4 but an elevated level of LF and LT alpha G. It has been established that HS is more active than ES or IS, and it influences the mechanisms of humoral immunity.
View Article and Find Full Text PDFThe immunofluorescence techniques with monospecific antibodies to lactoferrin (LF) and leukocytic thermostable alpha-glycoprotein (LT alpha-G) has demonstrated that both the proteins are specific components of the peripheral blood granulocytes of normal subjects. LF and LT alpha-G are detectable in the cytoplasmic granules of polynuclear leukocytes but not on the external surface of these cells' membranes. Differences between the direct and indirect immunofluorescence techniques, used for the detection of the granulocytic LF and LT alpha-G are discussed.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!