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[Thrombosis in Hemodialysis Tunnelled Central Venous Catheters: From Pathogenesis to Therapeutic Strategies].
G Ital Nefrol
October 2024
U.O.C. di Nefrologia e Dialisi, Ospedale Generale Regionale "F. Miulli", Acquaviva delle Fonti (BA).
Central venous catheter-related thrombosis is a frequent non-infectious complication, typically associated with catheter dysfunction and hemodialysis inadequacy. Central venous catheters (CVCs) are categorized into non-tunnelled and tunnelled types, wherein the choice depends on patient's clinical conditions and the diagnostic and therapeutic workup. Tunnelled CVCs (tCVCs) are sought whenever an arteriovenous fistula is unfeasible or as primary access in patients with poor prognosis.
View Article and Find Full Text PDFAbility of Activated Clotting Time Measurements to Monitor Unfractionated Heparin Activity During NonCardiac Arterial Procedures.
Ann Vasc Surg
January 2025
Department of Vascular Surgery, Amsterdam UMC, Location VUmc, Amsterdam, The Netherlands; Department of Vascular Surgery, Dijklander Ziekenhuis, Hoorn, The Netherlands; Amsterdam Cardiovascular Sciences, Microcirculation, Amsterdam, The Netherlands. Electronic address:
Background: Activated clotting time (ACT) measurements are frequently used to monitor unfractionated heparin activity during noncardiac arterial procedures (NCAP). Accuracy of ACT-guided heparinization is mandatory to prevent heparin under and overdosing, thereby minimizing thrombo-embolic complications (TECs) and bleeding risk. The main objective of this study was to investigate accuracy of ACT to monitor heparin activity during NCAP using the Hemostasis Management System Plus (HMS) with high-range (HR) cartridges.
View Article and Find Full Text PDFNew-onset atrial fibrillation after coronary surgery and stroke risk: a nationwide cohort study.
Heart
December 2024
Department of Molecular and Clinical Medicine, Sahlgrenska Academy, Goteborg, Sweden.
Article Synopsis
- * Among over 10,000 patients with POAF, those not taking oral anticoagulation (OAC) had a 3.1% risk of ischaemic stroke within one year, with factors like age, prior stroke, myocardial infarction, and heart failure significantly increasing stroke risk.
- * The ATRIA score showed slightly better predictive ability for stroke risk compared to the CHADS-VASc score, but many patients
Management of Portal vein Thrombosis in Cirrhosis.
Semin Liver Dis
November 2024
Department of Hepatology, Institute of Liver and Biliary Sciences, Vasant Kunj, New Delhi, India.
Portal vein thrombosis (PVT) is one of the common complications of cirrhosis. The incidence of PVT correlates with liver disease severity-higher incidence in patients with Child-Turcotte-Pugh (CTP) C, large spontaneous portosystemic shunts, hepatofugal portal flow, and in the presence of hepatocellular carcinoma. PVT may worsen ascites, increase the risk and poor control of variceal bleeding.
View Article and Find Full Text PDFImaging and Biomarkers: The Assesment of Pulmonary Embolism Risk and Early Mortality.
Medicina (Kaunas)
September 2024
1st Medical Department "Grigore T. Popa" University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.
: Pulmonary embolism (PE) incidence has been increasing in the last 10 years. Computed thoracic pulmonary angiography (CTPA) had a major role in PE diagnosis and prognosis. The main purpose of this study was as follows: the prognostic value of a CTPA parameter, pulmonary artery obstruction index (PAOI), in PE risk assessment and the predictive accuracy of biomarkers, D-dimer and cardiac Troponin T (c-TnT), in 7-day mortality.
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