A 31-year-old male was transferred to our hospital with severe heart failure due to viral myocarditis. He progressed to multiorgan failure requiring intubation and maximal doses of multiple vasopressors. Circulatory support was provided with an Impella device as a bridge to an extracorporeal membrane oxygenation (ECMO) system. On full mechanical cardiovascular support, the patient's hemodynamic status improved and ECMO and Impella were explanted after 48 hours. Three days later, he was extubated and continued on to a full recovery. There are no specific therapies for fulminant myocarditis but first-line treatment is supportive care. ECMO is commonly used in patients with severe heart failure. In severe systolic dysfunction, left ventricular decompression is required to reduce myocardial wall stress, decrease myocardial oxygen requirements, and enhance the chances of recovery. The Impella, an active support system, is less invasive than classical decompressive techniques and is associated with lower requirements for blood products with fewer thromboembolic complications. This is the only case reported of the contemporary use of Impella and ECMO as a bridge to full recovery in an adult with myocarditis. It also presents a novel use of the Impella device in decompressing the left ventricle of an adult patient on ECMO.
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http://dx.doi.org/10.1155/2012/459296 | DOI Listing |
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Research Unit on Youth, Physical Activity, Sports and Health (J-AP2S), University of Toulon, Toulon, France.
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Fourier ptychographic microscopy (FPM) can provide high-throughput imaging by computationally combining low-resolution images at different spatial frequencies within the Fourier domain. The core algorithm for FPM reconstruction draws upon phase retrieval techniques, including methods such as the ptychographic iterative engine (PIE), regularized PIE (rPIE), and embedded pupil function FPM (EPRY-FPM). The calibration of the physical setup plays a crucial role in the quality of the reconstructed high space-bandwidth product (SPB) image.
View Article and Find Full Text PDFNeurophysiol Clin
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