A healthy 21-year-old primigravida presented for elective cesarean section. At 45 min after intrathecal (IT) injection of bupivacaine, morphine and fentanyl she developed dysphagia, right sided facial droop, ptosis and ulnar nerve weakness. This constellation of signs and symptoms resolved 2 h later. Based on the time course and laterality of her symptoms, as well as the pharmacologic properties of spinal opioids, we believe her symptoms can be attributed to the IT administration of fentanyl.
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http://dx.doi.org/10.4103/0970-9185.130073 | DOI Listing |
J Oral Maxillofac Surg
January 2025
Research Assistant, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Ondokuz Mayıs University, Samsun, Turkey. Electronic address:
Background: Arthrocentesis is a minimally invasive procedure for treating intra-articular temporomandibular disorders. While it is considered relatively safe, like any surgical intervention, it carries potential risks.
Purpose: The study purpose was to estimate the frequency of complications associated with temporomandibular joint arthrocentesis, identify risk factors, and improve preparedness for effective prevention and management strategies.
Am J Ophthalmol
January 2025
Raghudeep Eye Hospital, Laden Cataract and IOL research centre, Ahmedabad, India 380052.
Purpose: To evaluate demographic profile, risk factors and outcomes following intraocular lens (IOL) exchange surgery for late decentration of IOLs in the dead bag syndrome DESIGN: Prospective, interventional case series PARTICIPANTS: 46 eyes (43 patients) with late decentration/dislocation of IOLs and spontaneous posterior capsule rupture in a clear and relatively intact capsular bag. None of the eyes had significant zonular weakness.
Methods: Study conducted at Raghudeep Eye Hospital, India.
AJNR Am J Neuroradiol
January 2025
Department of Pediatric Radiology and Neuroradiology (C.D., F.A., C.P., A.R.), Children's Hospital V. Buzzi, Milan, Italy.
Glucose transporter type 1 deficiency syndrome (GLUT1-DS) is an uncommon condition represented by an infantile-onset disorder, frequently arising from heterozygous mutations in the gene. Individuals with GLUT1-DS may present with early-onset seizures (typically manifesting before 4 years of age), developmental delay, and complex movement disorders. In fewer cases, stroke-like events or hemiplegic migraine-like symptoms are also reported, defined by unilateral paresis affecting 1 side of the body and/or one-half of the face, occasionally accompanied by speech impairment.
View Article and Find Full Text PDFCureus
December 2024
Internal Medicine, Saint Joseph Hospital-Intermountain Health, Denver, USA.
The pupillary reflex is a complex physiological response involving both the eye and associated neural pathways. Relative afferent pupillary defects (RAPDs) can present due to various underlying pathologies, yet their occurrence in serotonin syndrome has been rarely documented. This report details the case of a 21-year-old non-binary individual with a history of bipolar disorder who presented to the emergency department following a polypharmacy overdose, including significant ingestion of sertraline, aripiprazole, and buspirone.
View Article and Find Full Text PDFJ Clin Med
December 2024
Department of Correct, Clinical and Imaging Anatomy, Medical University of Lublin, ul. Jaczewskiego 4, 20-090 Lublin, Poland.
As speech-related symptoms of Landau-Kleffner syndrome (LKS) are often refractory to pharmacotherapy, and resective surgery is rarely available due to the involvement of the vital cortex, multiple subpial transection (MST) was suggested to improve patient outcome and preserve cortical functions. Here, we analyze the reports about MST use in LKS, regarding its impact on seizures, language, behavior, EEG, cognition, and reported adverse effects. In conditions like LKS, surgery is not a popular treatment option and presumably should be considered sooner.
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