Vocabulary is an appropriate measure of premorbid intelligence in a sample with heterogeneous educational level in Brazil.

Behav Neurol

Behavioral and Cognitive Neurology Unit, Faculdade de Medicina da Universidade de São Paulo (FMUSP), 255 Avenue Dr. Enéas de Carvalho Aguiar, São Paulo 05403-900, SP, Brazil ; Cognitive Disorders Reference Center (CEREDIC), Faculdade de Medicina da Universidade de São Paulo (FMUSP), 206 Rua Arruda Alvim, Cerqueira Cesar, São Paulo 05419-020, SP, Brazil ; Santa Marcelina Hospital, Neurology Department, 360 Rua Santa Marcelina, Vila Carmosina, São Paulo 08270-070, SP, Brazil.

Published: December 2014

Crystallized intelligence refers to one's knowledge base and can be measured by vocabulary tests. Fluid intelligence is related to nonverbal aspects of intelligence, depends very little on previously acquired knowledge, and can be measured by tests such as Block Design (BD) and Raven Colored Matrices (RCM). Premorbid intelligence quotient (IQ) refers to one's intellectual ability level previous to the onset of disorders like mild cognitive impairment (MCI) and Alzheimer's disease (AD) and it is important to estimate disease severity. The objective was to compare performance in tests that measure crystallized and fluid intelligence in healthy subjects and patients with amnestic MCI (aMCI) and AD. One hundred forty-four participants (aMCI (n = 38), AD (n = 45), and healthy controls (n = 61)) were submitted to neuropsychological tests (WAIS-III vocabulary, BD, and RCM). There were significant among groups, except for vocabulary, indicating a relative stability of crystallized intelligence in the continuum from normal to pathological cognitive decline. Vocabulary seems to be stable during the progression of the disease and useful as a measure of premorbid intelligence, that is, to estimate previous function in relation to the level of education and, as a collateral measure of cognition in people with low education.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006600PMC
http://dx.doi.org/10.1155/2014/875960DOI Listing

Publication Analysis

Top Keywords

premorbid intelligence
12
measure premorbid
8
intelligence
8
crystallized intelligence
8
refers one's
8
fluid intelligence
8
vocabulary
5
vocabulary appropriate
4
measure
4
appropriate measure
4

Similar Publications

Mathematical modeling of impacts of patient differences on renin-angiotensin system and applications to COVID-19 lung fibrosis outcomes.

Comput Biol Med

January 2025

Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, 14260, USA; Department of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, NY, 14260, USA; Institute for Artificial Intelligence and Data Science, University at Buffalo, The State University of New York, Buffalo, NY, 14260, USA; Witebsky Center for Microbial Pathogenesis and Immunology, University at Buffalo, The State University of New York, Buffalo, NY, 14203, USA; Department of Pharmaceutical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, 14215, USA. Electronic address:

Article Synopsis
  • Patient-specific factors like age, sex, and existing health conditions significantly impact the severity of lung diseases, including COVID-19-related fibrosis, with the renin-angiotensin system (RAS) playing a key regulatory role.
  • Recent studies show conflicting results regarding changes in RAS peptides post-SARS-CoV-2 infection, necessitating a multiscale computational model that integrates various factors to assess the systemic effects of RAS during COVID-19.
  • The model indicates that inflammation leads to reduced ACE and ACE2 levels, with variations in RAS peptide changes across different patient demographics, suggesting potential for personalized treatment approaches in lung disease management.
View Article and Find Full Text PDF

Objective: to study the features of cognitive disorders in the remote period following exposure to ionizing radiation (IR) in the elderly participants of the liquidation of the consequences of the Chornobyl NPP accident (Chornobyl clean-up workers) with chronic cerebrovascular disorders.

Materials And Methods: The retrospective and prospective cohort study with the external and internal controlgroups. The randomized sample of the male elderly participants (attained age more than 60 years old) in liquidationof the consequences of the accident (Chornobyl clean-up workers, liquidators) at the Chornobyl nuclear power plant(ChNPP) in 1986-1987 (main group, n = 52) recruited from the Clinico-epidemiological registry (CER) of StateInstitution «National Research Center for Radiation Medicine, Hematology and Oncology of The National Academyof Medical Sciences of Ukraine» (NRCRMHO) with verified chronic cerebrovascular disorders (CVD) was examined.

View Article and Find Full Text PDF

Objective: Large language models (LLMs) have recently gained attention for clinical decision-making and diagnosis. This study evaluates the performance of the recently updated LLM (ChatGPT-4o) in predicting clinical outcomes in patients with status epilepticus and compares its prognostic performance to the Status Epilepticus Severity Score (STESS).

Methods: This retrospective single-center cohort study was performed at the University Hospital Basel (tertiary academic medical center) from January 2005 to December 2022.

View Article and Find Full Text PDF

Objective: To examine correlates of the discrepancy between subjective cognitive complaints and processing speed performance in a sample of military personnel with and without traumatic brain injury (TBI).

Method: About 235 U.S.

View Article and Find Full Text PDF

Mismatch negativity (MMN) has gained attention as a biomarker for psychosis and a translational intermediate phenotype in animal models of psychosis, including rodents and non-human primates. MMN has been linked to global functioning (Global Assessment of Functioning [GAF] score) and prognosis (psychosis onset or remission), suggesting that MMN reflects activities beyond auditory processing alone. This review examines the 45-year history of MMN from the perspective of psychiatric researchers and discusses current advances in computational and translational research on MMN, summarizing the current understanding of the MMN generation mechanism.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!