An elegant route for hydroxyapatite (HA) particle synthesis via ionic exchange reaction is reported. Calcium carbonate particles (CaCO3) were recrystallized into HA beads in water solution with phosphate ions. The size of initial CaCO3 particles was controlled upon the synthesis by varying the amount of ethylene glycol (EG) in aqueous solution. The average size of HA beads ranged from 0.6±0.1 to 4.3±1.1μm. Silver nanoparticles were deposited on the surface of HA and CaCO3 particles via silver mirror reaction. Surface enhanced Raman scattering of silver functionalized beads was demonstrated by detecting Rhodamine B. CaCO3 and HA particles have a great potential for design of carrier which can provide diagnostic and therapeutic functions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.colsurfb.2014.03.053 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A comparative X-ray diffraction analysis of Srsubstituted hydroxyapatite from sand lobster shell waste using various methods.
Heliyon
January 2025
Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Yogyakarta, 55281, Indonesia.
This study aims to investigate the crystallographic properties of hydroxyapatite (HAp) and strontium-substituted hydroxyapatite (SrHAp) obtained from sand lobster shells (SLS) using various analytical methods. HAp and SrHAp were synthesized by the hydrothermal method using sand lobster () shell waste as a calcium precursor. SLS were calcined at 0 °C, 600 °C, 800 °C, and 1000 °C and characterized by X-ray diffraction (XRD).
View Article and Find Full Text PDFThe nucleolin antagonist N6L and paclitaxel combination treatment could be a new promising therapeutic strategy for pancreatic ductal adenocarcinoma therapy.
Eur J Pharmacol
January 2025
Université Paris-Est, Immunorégulation et Biothérapie, INSERM U955, Hôpital Henri Mondor, 94010 Créteil, France; AP-HP, Groupe hospitalo-universitaire Chenevier Mondor, Centre d'investigation clinique Biotherapie, F-94010 Creteil, France. Electronic address:
Pancreatic cancer (PCa) is one of the most devastating cancers with few clinical signs and no truly effective therapy. In recent years, our team has demonstrated that nucleolin antagonists such as N6L could be a therapeutic alternative for this disease. In order to study a possible clinic development of N6L (multivalent pseudopeptide), we undertook to study the effect of combination of N6L with chemotherapies classically used for PCa on the survival of pancreatic cancer cells.
View Article and Find Full Text PDFEnhancing Polylactic Acid (PLA) Performance: A Review of Additives in Fused Deposition Modelling (FDM) Filaments.
Polymers (Basel)
January 2025
Materials Engineering and Welding Department, Transilvania University of Brasov, 500036 Brasov, Romania.
This review explores the impact of various additives on the mechanical properties of polylactic acid (PLA) filaments used in Fused Deposition Modeling (FDM) 3D printing. While PLA is favored for its biodegradability and ease of use, its inherent limitations in strength and heat resistance necessitate enhancements through additives. The impact of natural and synthetic fibers, inorganic particles, and nanomaterials on the mechanical properties, printability, and overall functionality of PLA composites was examined, indicating that fiber reinforcements, such as carbon and glass fibers, significantly enhance tensile strength and stiffness, while natural fibers contribute to sustainability but may compromise mechanical stability.
View Article and Find Full Text PDF[Preparation of multi-layer compound microcapsules and their application in self-healing of concrete cracks].
Sheng Wu Gong Cheng Xue Bao
January 2025
College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, Zhejiang, China.
Concrete is widely used in building construction, civil engineering, roads, bridges, etc., but concrete cracking remains a major issue in the engineering industry. To develop an effective and feasible concrete repair technology, this study combined microbial and microencapsulation technologies to prepare a multi-layer compound microcapsule using the piercing method.
View Article and Find Full Text PDFCombining Hard Shell with Soft Core to Enhance Enzyme Activity and Resist External Disturbances.
Adv Sci (Weinh)
January 2025
Department of Cardiology, The First People's Hospital of Wenling, Wenling Hospital of Wenzhou Medical University, Wenling, Zhejiang, 317500, China.
Immobilizing enzymes onto solid supports having enhanced catalytic activity and resistance to harsh external conditions is considered as a promising and critical method of broadening enzymatic applications in biosensing, biocatalysis, and biomedical devices; however, it is considerably hampered by limited strategies. Here, a core-shell strategy involving a soft-core hexahistidine metal assembly (HmA) is innovatively developed and characterized with encapsulated enzymes (catalase (CAT), horseradish peroxidase, glucose oxidase (GOx), and cascade enzymes (CAT+GOx)) and hard porous shells (zeolitic imidazolate framework (ZIF), ZIF-8, ZIF-67, ZIF-90, calcium carbonate, and hydroxyapatite). The enzyme-friendly environment provided by the embedded HmA proves beneficial for enhanced catalytic activity, which is particularly effective in preserving fragile enzymes that will have been deactivated without the HmA core during the mineralization of porous shells.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!