Objectives: We aimed to evaluate the long-term prognosis of prophylactic repair of the descending aorta using the frozen elephant trunk (FET) technique for acute type A aortic dissection (AAAD).
Methods: Between 1997 and 2012, 120 consecutive patients (mean age: 64.4 ± 10.9 years) underwent total arch replacement with FET for AAAD; 36 patients had an entry at the descending aorta, 68 patients were aged <70 years and 8 patients had Marfan's syndrome. With regard to preoperative morbidity, 23 patients had stroke, 10 had coronary ischaemia and 9 had visceral ischaemia. During intraoperative measurement, the required size and length of the stent graft were determined and inserted under transoesophageal echographic guidance.
Results: Seven patients (6%) died in the hospital. Four (3%) cases of stroke and 2 (2%) with spinal cord injuries were noted. Computed tomography prior to discharge indicated complete thrombosis of the false lumen by the stent graft in 113 patients, with a mean diameter of 26.0 ± 2.5 mm before discharge and 27.5 ± 2.5 mm at 1 year postoperatively compared with a mean stent graft diameter of 27.8 ± 1.7 mm. During the long-term follow-up (mean period: 104.6 ± 51.9 months), 12 patients died of non-aortic events and 5 distal aortic reoperations were required using endovascular stent grafting of the descending aorta, including 1 case with new tear formation. None of the patients had a patent false lumen on the stent graft at the final follow-up. The 10-year survival rate was 75% and the overall 10-year reoperation-free rate on the thoracic aorta was 93%.
Conclusions: The FET technique results in excellent aortic remodelling of the downstream aorta and can improve the long-term outcomes for AAAD.
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http://dx.doi.org/10.1093/ejcts/ezu173 | DOI Listing |
Ann Vasc Dis
December 2024
Cardiovascular and Thoracic Center, Viet Duc University Hospital, Hanoi, Vietnam.
We evaluate the preliminary and intermediate-term results of Viet Duc modification of the frozen elephant trunk (FET) technique. During December 2019 and May 2023, 47 patients underwent surgery using our modification of the FET at Viet Duc University Hospital. The mean age of the patients was 56.
View Article and Find Full Text PDFMethodsX
December 2024
Mammal Research Institute, Department of Zoology and Entomology, University of Pretoria, 0028 Hatfield, South Africa.
Monitoring stress-related faecal glucocorticoid metabolite (fGCM) concentrations is a reliable, popular and established approach for understanding wildlife responses to perceived stressors. To maintain fGCM integrity post-defaecation, faecal material must be promptly stored frozen, or dried to prevent continued suspected bacterial enzyme activity. We compare the effectiveness of freeze-drying with other field-friendly drying techniques (food dehydrator and homemade solar oven).
View Article and Find Full Text PDFJ Vasc Surg Cases Innov Tech
February 2025
Department of Cardio-Thoracic Surgery, Radboud Umc, Nijmegen, The Netherlands.
We describe a case of retrograde acute type A aortic dissection approached by a hybrid, staged approach consisting of a zone 2 arch replacement and completion thoracic endovascular aortic repair procedure combined with distal balloon-assisted stent graft dilatation to prevent retrograde false lumen flow. This technique may be an alternative and more complete when compared with a frozen elephant trunk procedure at onset. Additionally, favorable remodeling of the entire thoracic aorta is observed.
View Article and Find Full Text PDFJ Clin Med
December 2024
CAROL-Cardiothoracic Anatomy Research Operative Lab, Department of Cardiovascular Surgery and Transplantology, Institute of Cardiology, Jagiellonian University Medical College, 31-008 Kraków, Poland.
Spinal cord ischemia is one of the most serious complications after an aortic repair. To date, there is no evidence for arterial changes during an aortic dissection or for the observation of such arteries after an aortic repair. The aim of this study was to compare spinal-cord-supplying arteries in patients with an acute aortic dissection, preoperatively and postoperatively, with patients without an acute aortic dissection.
View Article and Find Full Text PDFJ Clin Med
November 2024
Department of Cardiac Surgery, CINRE Hospital, 84103 Bratislava, Slovakia.
The involvement of the aortic arch in thoracic aortic aneurysms (TAA), or acute aortic dissections (AAD), represents a challenging clinical entity, mandating a meticulous surgical plan, tailored to each individual case. The advent of endovascular techniques and the introduction of modern arch protheses have led to the implementation of the frozen elephant trunk (FET) technique. This one-step hybrid operation consists of a total aortic arch replacement combined with an antegrade delivery of a stent-graft for the descending aorta, which acts as a proximal landing zone facilitating a potential distal endovascular reintervention.
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