Macro and small over micro: macromolecules and small molecules that regulate microRNAs.

Chembiochem

Department of Pharmacy, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul 156-756 (Korea).

Published: May 2014

Given the correlation between the deregulation of specific miRNAs and disease onset, it is critical to identify miRNA regulators that effectively control miRNAs involved in the pathogenesis of target diseases. This review provides the latest update on oligonucleotide- and small-molecule-based miRNA regulators, and discusses assays developed to screen for small-molecule regulators.

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Source
http://dx.doi.org/10.1002/cbic.201402007DOI Listing

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