Introduction: The objective of this trial is to investigate the diagnostic value of magnetic resonance imaging (MRI) with an endorectal surface coil for precise local staging of patients with histologically proven cervical cancer by comparing the radiological, clinical, and histological results.
Materials And Methods: Women with cervical cancer were recruited for this trial between February 2007, and September 2010. All the patients were clinically staged according to the FIGO classification and underwent radiological staging by MRI that employed an endorectal surface coil. The staging results after surgery were compared to histopathology in all the operable patients.
Results: A total of 74 consecutive patients were included in the trial. Forty-four (59.5%) patients underwent primary surgery, whereas 30 (40.5%) patients were inoperable according to FIGO and underwent primary radiochemotherapy. The mean age of the patients was 50.6 years. In 11 out of the 44 patients concordant staging results were obtained by all three staging modalities. Thirty-two of the 44 patients were concordantly staged by FIGO and histopathological examination, while only 16 were concordantly staged by eMRI and histopathological examination. eMRI overstaged tumors in 14 cases and understaged them in 7 cases.
Conclusions: eMRI is applicable in patients with cervical cancer, yet of no benefit than staging with FIGO or standard pelvic MRI. The most precise preoperative staging procedure still appears to be the clinical examination.
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http://dx.doi.org/10.1016/j.ejrad.2014.02.011 | DOI Listing |
Radiol Adv
September 2024
Medical Biophysics, Western University, London, N6A 3K7, Canada.
Background: Sodium (Na) MRI of prostate cancer (PCa) is a novel but underdocumented technique conventionally acquired using an endorectal coil. These endorectal coils are associated with challenges (e.g.
View Article and Find Full Text PDFIEEE Trans Biomed Eng
December 2023
Objective: The purpose of this work is to develop a 3-channel endorectal coil (ERC-3C) structure to obtain higher signal-to-noise (SNR) and better parallel imaging performance for prostate magnetic resonance imaging (MRI) at 3T.
Methods: The coil performance was validated by in vivo studies and the SNR, g-factor, and diffusion-weighted imaging (DWI) were compared. A 2-channel endorectal coil (ERC-2C) with two orthogonal loops and a 12-channel external surface coil were employed for comparison.
Med Phys
July 2023
Department of Radiation Oncology, Mayo Clinic Arizona, Phoenix, Arizona, USA.
Background: Deep learning auto-segmentation (DLAS) models have been adopted in the clinic; however, they suffer from performance deterioration owing to the clinical practice variability. Some commercial DLAS software provide an incremental retraining function that enables users to train a custom model using their institutional data to account for clinical practice variability.
Purpose: This study was performed to evaluate and implement the commercial DLAS software with the incremental retraining function for definitive treatment of patients with prostate cancer in a multi-user environment.
Magn Reson Imaging
September 2023
Computational BioMedicine Laboratory (CBML), Institute of Computer Science, Foundation for Research and Technology - Hellas (FORTH), Heraklion, Greece; Department of Electrical & Computer Engineering, Hellenic Mediterranean University, Heraklion, Greece.
Magnetic Resonance (MR) images suffer from spatial inhomogeneity, known as bias field corruption. The N4ITK filter is a state-of-the-art method used for correcting the bias field to optimize MR-based quantification. In this study, a novel approach is presented to quantitatively evaluate the performance of N4 bias field correction for pelvic prostate imaging.
View Article and Find Full Text PDFBrachytherapy
December 2022
Department of Radiation Oncology (MAASTRO), GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands. Electronic address:
Introduction: The various rectal endoluminal radiation techniques all have steep, but different, dose gradients. In rectal contact brachytherapy (CXB) doses are typically prescribed and reported to the applicator surface and not to the gross tumor volume (GTV), clinical target volume (CTV) or organs at risk (OAR), which is crucial to understand tumor response and toxicity rates. To quantify the above-described problem, we performed a dose modeling study using a fixed prescription dose at the surface of the applicator and varied tumor response scenarios.
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