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Unveiling Poncet Disease: A Rare Presentation with Multiple Tubercular Foci in the Hand and Spine of an Older Patient: A Case Report.
J Hand Surg Asian Pac Vol
December 2024
Department of Orthopaedic Surgery, Kindai University Hospital, Osaka-Sayama City, Osaka, Japan.
Article Synopsis
- Poncet disease (PD) is a rare condition linked to acute tuberculosis that impacts joints, specifically noted in a 76-year-old patient with symptoms in the hands and spine.
- Radiographic imaging identified destructive bone lesions in the trapezium and spine, leading to a biopsy that confirmed TB-related damage.
- The case emphasizes the need to consider PD in elderly patients showing multiple TB foci, particularly affecting the hands, and the patient was referred to a specialized TB facility for treatment.
Tubercular arachnoiditis: A rare culprit of paraparesis in a young adult - A case report and review of literature.
Surg Neurol Int
November 2024
Department of Neurosurgery, Nil Ratan Sircar Medical College and Hospital, Kolkata, West Bengal, India.
Background: The prevalence of central nervous system tuberculosis (TB) is about 1-2% of all TB cases. Atypical cases like the present case, being interpreted as leptomeningeal metastasis in magnetic resonance imaging (MRI), can pose a dilemma, delaying or even leading to mistreatment.
Case Description: A 19-year-old male presented with acute onset paraparesis and bowel bladder involvement presented with an MRI lumbar spine suggesting leptomeningeal metastasis from D11-L5 levels who underwent decompression biopsy which on histopathological examination revealed to be tubercular granulomatous infection.
What Is the Accuracy of 16S PCR Followed by Sanger Sequencing or Next-generation Sequencing in Native Vertebral Osteomyelitis? A Systematic Review and Meta-analysis.
Clin Orthop Relat Res
December 2024
Division of Public Health, Infectious Diseases and Occupational Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Mayo Clinic, Rochester, MN, USA.
Article Synopsis
- - Identifying bacteria in native vertebral osteomyelitis is difficult due to slow culture methods and varying accuracy of molecular diagnostics like 16S PCR and metagenomic sequencing, creating uncertainty in their clinical effectiveness.
- - A study conducted in 2023 reviewed data from January 1970 to June 2023 to evaluate the sensitivity, specificity, and diagnostic odds ratios of these molecular methods in adults suspected of having this condition, excluding certain types of osteomyelitis.
- - Out of 3403 studies reviewed, 10 were selected for analysis based on strict criteria, ultimately involving 391 patients, revealing moderate risk of bias but good applicability for diagnosing native vertebral osteomyelitis.
Cranio-vertebral junction tuberculosis: Uncommon presentation of a common disease.
J R Coll Physicians Edinb
November 2024
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India.
Article Synopsis
- Cranio-vertebral junction (CVJ) tuberculosis is a rare but serious condition that can lead to significant health issues.
- A case study of a young woman showed she experienced headaches, neck pain, and weight loss, with diagnosis confirmed through clinical assessment and imaging.
- Treatment included anti-tubercular medication and using a cervical collar for support, leading to notable improvement, highlighting the effectiveness of conservative treatments for this complex condition.
Spondylodiscitis and Its Mimickers: A Pictorial Review.
Biomedicines
November 2024
Department of Radiology, National Institute for Infectious Disease "Lazzaro Spallanzani", 00149 Rome, Italy.
Spondylodiscitis is an infection of the intervertebral disc, the adjacent vertebral body, and/or contiguous structures due to the introduction of infectious agent, usually by the hematogenous route. Imaging is crucial in assessing bacterial and tubercular spondylodiscitis, as well as their associated complications. Magnetic resonance imaging in particular can clearly depict osteo-structural changes in the vertebral body and the associated disc, as well as any soft-tissue complications, such as paravertebral abscess and/or epidural abscess, improving disease characterization and helping to recognize the agent involved.
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