Objective: Despite its long and auspicious place in the history of psychiatry, dissociative identity disorder (DID) has been associated with controversy. This paper aims to examine the empirical data related to DID and outline the contextual challenges to its scientific investigation.
Methods: The overview is limited to DID-specific research in which one or more of the following conditions are met: (i) a sample of participants with DID was systematically investigated, (ii) psychometrically-sound measures were utilised, (iii) comparisons were made with other samples, (iv) DID was differentiated from other disorders, including other dissociative disorders, (v) extraneous variables were controlled or (vi) DID diagnosis was confirmed. Following an examination of challenges to research, data are organised around the validity and phenomenology of DID, its aetiology and epidemiology, the neurobiological and cognitive correlates of the disorder, and finally its treatment.
Results: DID was found to be a complex yet valid disorder across a range of markers. It can be accurately discriminated from other disorders, especially when structured diagnostic interviews assess identity alterations and amnesia. DID is aetiologically associated with a complex combination of developmental and cultural factors, including severe childhood relational trauma. The prevalence of DID appears highest in emergency psychiatric settings and affects approximately 1% of the general population. Psychobiological studies are beginning to identify clear correlates of DID associated with diverse brain areas and cognitive functions. They are also providing an understanding of the potential metacognitive origins of amnesia. Phase-oriented empirically-guided treatments are emerging for DID.
Conclusions: The empirical literature on DID is accumulating, although some areas remain under-investigated. Existing data show DID as a complex, valid and not uncommon disorder, associated with developmental and cultural variables, that is amenable to psychotherapeutic intervention.
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http://dx.doi.org/10.1177/0004867414527523 | DOI Listing |
Life Sci
January 2025
Immuno-Endocrinology, Diabetes & Metabolism Laboratory, Instituto de Investigaciones en Medicina Traslacional (IIMT), CONICET - Universidad Austral, Pilar, Argentina; Facultad de Ciencias Biomédicas, , Universidad Austral, Pilar, Argentina. Electronic address:
Aims: Type 2 diabetes (T2D) is a prevalent metabolic disease linked to obesity and metabolic syndrome (MS). The glucolipotoxic environment (GLT) impacts tissues causing low-grade inflammation, insulin resistance and the gradual loss of pancreatic β-cell function, leading to hyperglycemia. We have previously shown that Compound A (CpdA), a plant-derived dissociative glucocorticoid receptor-modulator with inflammation-suppressive activity, displays protective effects on β-cells in type 1 diabetes murine models.
View Article and Find Full Text PDFHarv Rev Psychiatry
January 2025
From School of Social Sciences, University of New South Wales (Dr. Salter); Department of Psychology, Towson University (Dr. Brand); Harvard Medical School (Dr. Robinson); School of Medicine, University of Maryland (Dr. Loewenstein); The Leadership Council on Child Abuse & Interpersonal Violence, Towson, MD (Dr. Silberg); Faculty of Health Sciences, McMaster University (Dr. Korzekwa).
Recent global popularity of social media content about dissociative identity disorder (DID) has coincided with increased self-diagnosis among children and young people who have formed large online communities and presented in clinical settings seeking to affirm their self-diagnoses. We situate this phenomenon within a broader trend toward self-diagnosis due to the widespread visibility and accessibility of mental health content on social media. Social media propelled self-diagnosis raises particular questions for the study and treatment of DID due to long-standing debates over whether the condition is traumagenic, sociogenic, or iatrogenic.
View Article and Find Full Text PDFJ Trauma Dissociation
January 2025
Solo Private Practice, Wauwatosa, Wisconsin.
The abusive and/or neglectful relational mis-attunement disrupts ongoing developmental growth and binds attachments to abusive caregivers. This shame-based relational frame then becomes a template for subsequent relationships and self-definitions. Shame and dissociation combine to provide a paradoxical and powerful self-protective form of self-regulation via a dis-enlivened existence that enables people with DID to live with otherwise potentially dysregulating affects and relationships.
View Article and Find Full Text PDFCureus
November 2024
Department of Public Health and Environmental Medicine, The Jikei University School of Medicine, Tokyo, JPN.
Little is known about the effectiveness of pharmacotherapy in dissociative identity disorder (DID). Zinc is essential for proper brain function. Its deficiency can lead to mental health symptoms, possibly contributing to dissociation.
View Article and Find Full Text PDFFront Psychiatry
December 2024
Insititute of Psychology, SWPS University, Warsaw, Poland.
Introduction: In recent years there has been a notable expansion of psychotherapeutic approaches to treat people experiencing auditory verbal hallucinations (AVH). While many psychotherapists conceptualize voices as "dissociative parts" and apply therapeutic techniques derived from the field of dissociation, research investigating AVH from this perspective is limited. Despite the acknowledgment that voices encountered in dissociative identity disorder (DID) often exhibit high complexity and autonomy, there is a critical need for assessment tools capable of exploring voice complexity across different clinical groups.
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