Background: Ferritin is the storage form of iron. Hence, the sensitive test which can be used for diagnosing iron deficiency anaemia is estimation of ferritin in serum. One of the causative factors of oral ulceration is nutritional deficiency, which includes iron also.
Aim: To study the meaningful association between recurrent oral ulcer and ferritin.
Materials And Methods: Fifty oral ulcer cases which were diagnosed clinically in the ENT Department of Sree Balaji Medical College and Hospital and Twenty Five controls were included in this study. Serum ferritin was estimated by doing a particle enhanced turbidimetric immunoassay for both cases and controls.
Results: 66% of cases had decreased ferritin values and 34% had normal values, which was significant.
Conclusion: From this study, it can be concluded that it is mandatory to screen oral ulcer patients for iron deficiency anaemia by estimating serum ferritin and it is also advisable for the patients to have iron supplementation on regular basis, along with diet rich in iron in addition to vitamins.
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http://dx.doi.org/10.7860/JCDR/2014/7472.4091 | DOI Listing |
Nurs Crit Care
March 2025
Gulhane Faculty of Nursing, Department of Fundamentals of Nursing, University of Health Sciences, Ankara, Turkey.
Background: In intensive care units (ICUs), endotracheal tubes (ETTs) cause injury to the oral mucosa through friction and pressure. The incidence and risk factors of oral mucosal pressure injuries (PIs) have gained increasing attention in recent years.
Aim: The study aimed to identify risk factors for oral mucosal PIs associated with ETTs.
Glucocorticoids such as dexamethasone have shown promising therapeutic effects in conquering oral ulcers. Challenges in this area are focused on enhancing the localized curative effects and responsive release. Herein, we presented a novel MXene-integrated responsive hydrogel microneedle delivering dexamethasone to promote the healing of oral ulceration.
View Article and Find Full Text PDFArch Oral Biol
February 2025
Department of Stomatology, Xuzhou Clinical School of Xuzhou Medical University, Xuzhou, Jiangsu 221000, China; Department of Stomatology, Xuzhou Central Hospital, Xuzhou, Jiangsu 221000, China. Electronic address:
Objectives: This study aims to explore whether Connexin 43 (Cx43) in salivary extracellular vesicles (EVs) can serve as a biomarker for diagnosing oral lichen planus (OLP), an inflammatory oral mucosal disorder.
Design: The study assessed disease activity in OLP patients using the reticulum-erosion-ulcer disease activity score. Saliva EVs were isolated and purified with an EV Enrichment Kit.
Objectives: Systemic Lupus Erythematosus (SLE) can cause oral mucosal lesions, it is a severe autoimmune disease, manifesting as variable kinds of oral lesions. Occasionally, these clinical manifestations maybe be misdiagnosed as other diseases. The aim of the present article is to report a rare case of SLE oral mucosa lesions masquerading as an Erythema multiforme (EM) oral lesions in a young man.
View Article and Find Full Text PDFPharm Dev Technol
March 2025
Department of Pharmaceutics, Egyptian Drug Authority (EDA), Cairo, Egypt.
Objectives: Transnovasomes is a new exciting class of lipid-based nanovesicles. Colchicine (COL) is a hydrophilic natural alkaloid with anti-inflammatory features having oral administration and permeation defects. Recurrent Aphthous Ulcer (RAU) is the most prevalent disease of the oral mucosa suffering from lack of a particular and final preventative therapy.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!