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Dedifferentiated recurrent liposarcoma of the uterine corpus: A case report and literature review.
Case Rep Womens Health
December 2024
Department of Gynecology, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
Article Synopsis
- Liposarcoma of the uterine corpus is an extremely rare tumor with distinctive characteristics and treatment difficulties, as shown in a case study of a 57-year-old woman.
- The patient initially had surgery and chemotherapy after presenting with severe abdominal issues, but faced multiple recurrences over the following years, including a more aggressive form of the tumor.
- This case emphasizes the need for careful monitoring and individualized treatment plans to tackle the aggressive behavior of recurrent liposarcoma, particularly when it transforms into a dedifferentiated form.
Silent Giant: A Case of Dedifferentiated Retroperitoneal Liposarcoma Presenting as an Incidental Mesenteric Mass.
Cureus
October 2024
General Surgery, Sharon Regional Medical Center, Sharon, USA.
Article Synopsis
- - Dedifferentiated liposarcoma (DDL) is a rare and aggressive subtype typically found in the retroperitoneum, with challenging diagnostics, especially when it occurs in the mesentery as documented in very few cases.
- - A 76-year-old woman was discovered to have a large mesenteric mass incidentally while being treated for pneumonia, leading to surgery where a tumor adherent to the intestine was removed and identified as intermediate-grade DDL.
- - The case emphasizes the need to include mesenteric DDL in the differential diagnosis of large abdominal masses, highlighting that complete surgical resection is crucial for treatment, alongside regular follow-ups due to its aggressive nature.
Case report: a rare clinical presentation of a difficult diagnosis of dedifferentiated liposarcoma showing leiomyosarcoma phenotype in the ileocecal region.
Front Oncol
November 2024
Department of Orthopedic Surgery, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Chuo, Japan.
Dedifferentiated liposarcoma is a malignant lipomatous tumor that rarely occurs in the gastrointestinal tract, including the ileocecal region. In this case, computed tomography and magnetic resonance imaging showed no fatty mass located in the mesenteric or submucosal lesion, and positron emission tomography-computed tomography showed a high maximum standardized uptake value, collectively indicating the gastrointestinal stroma tumor and lymphoma. The pathological findings resemble leiomyosarcoma; the immunohistochemistry findings including mouse double minute 2 homolog and cyclin D-dependent kinase-4 and amplification of mouse double minute 2 homolog in fluorescence hybridization just favored the diagnosis of dedifferentiated liposarcoma with leiomyosarcoma phenotype and not leiomyosarcoma.
View Article and Find Full Text PDFA rare presentation of retroperitoneal liposarcoma presented with jejunal intussusception: An interesting radiological findings.
Radiol Case Rep
August 2024
Department of Surgery, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia.
A jejunal intussusception as a presentation of retroperitoneal liposarcoma (RLPS) is a rare occurrence. The majority of RLPS are presented as an abdominal mass, however, having a jejunal obstruction is an interesting case. The aim is to describe the management of jejunal intussusception secondary to atypical lipomatous tumours with concurrent RLPS.
View Article and Find Full Text PDF[Histoseminar tumoral peritoneal biopsies. Case No.1].
Ann Pathol
July 2024
Inserm U1209, CNRS UMR5309, Institut pour l'avancée des biosciences, service d'anatomie et cytologie pathologiques, CHU de Grenoble Alpes, University Grenoble Alpes, 38000 Grenoble, France. Electronic address:
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