Pulmonic regurgitation and management challenges in the adult with tetralogy of fallot.

Curr Treat Options Cardiovasc Med

University of Colorado, Denver ACHD Program, Leprino Office Building, B132, 12401 East 17th Avenue, Room 534, Aurora, CO, 80045, USA.

Published: June 2014

Patients with tetralogy of Fallot (TOF) are living longer than ever because of advances in surgery in childhood since the 1950s. However, surgery in childhood is not a cure and remains only a palliative procedure because almost all patients will require further intervention throughout life. The most common intervention required in adulthood is pulmonary valve replacement (PVR) because of residual pulmonary regurgitation leading to right ventricular dilation and eventual dysfunction. The most appropriate timing for PVR remains difficult to determine and is based on many factors. Our practice is to weigh not only objective factors such as right ventricular size and function but also careful objective assessment of the patient's current quality of life and functional status.

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Source
http://dx.doi.org/10.1007/s11936-014-0314-5DOI Listing

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