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ROLE OF AUTOLOGOUS NANOFAT GRAFTING IN THE TREATMENT OF POST ACNE AND POST BURN SCARRING OF THE FACE.
J Ayub Med Coll Abbottabad
December 2024
Burns & Plastic Surgery Centre, Hayatabad Medical Complex, Peshawar-Pakistan.
Background: Post acne and post burn facial scarring are more common in young generation leading to disfigurement and unpleasing result. These scars have major aesthetic, functional, and social effects on the affected person. Aim of the study was to establish the role of Autologous Nanofat grafting in treating post acne & post burn facial scarring in terms of pleasing aesthetic appearance of face & patient satisfaction.
View Article and Find Full Text PDFReconstruction of penile skin defect using negative pressure therapy, spiraling full-thickness skin grafts, and nanofat grafting: a case report.
J Surg Case Rep
November 2024
Plastic and Reconstructive Surgery Department, Hospital Universitario La Samaritana, Bogotá 110311, Colombia.
The penis is a structure that requires both anatomical and functional reconstruction. Being a three-dimensional structure that changes in volume, it presents a reconstructive challenge for the plastic surgeon. Currently, various alternatives are available for covering these complex defects, such as grafts, flaps, and dermal matrices.
View Article and Find Full Text PDFNanofat Improves Vascularization and Tissue Integration of Dermal Substitutes without Affecting Their Biocompatibility.
J Funct Biomater
October 2024
Institute for Clinical and Experimental Surgery, Saarland University, 66421 Homburg, Germany.
Dermal substitutes require sufficient tissue integration and vascularization to be successfully covered with split-thickness skin grafts. To rapidly achieve this, we provide the proof of principle for a novel vascularization strategy with high translational potential. Nanofat was generated from subcutaneous adipose tissue of green fluorescence protein (GFP) C57BL/6J donor mice and seeded onto small samples (4 mm in diameter) of the clinically approved dermal substitute Integra.
View Article and Find Full Text PDFEnrichment of Fat Graft with Association of ASC and Nanofat in an Animal Model.
Aesthetic Plast Surg
October 2024
Microsurgery and Plastic Surgery Laboratory (LIM-04), Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
Introduction: Fat graft (FG) absorption rate varies from 20 to 80% in two years. Recently, several bioengineering techniques were applied to improve FG retention rate. Numerous studies investigated the use of adipocyte-derived stem cells (ASC) as FG enrichment.
View Article and Find Full Text PDFEvaluating the Efficacy of Facial Scar Treatment Techniques Using Nanofat Grafting: A Case Series.
Cureus
September 2024
Department of Maxillofacial Surgery/Plastic Operations, Klinikum Oldenburg, Oldenburg, DEU.
Article Synopsis
- The appearance of atrophic scars, often caused by infections or inflammation from preoperative procedures, impacts patients' psychological and aesthetic quality.
- Recent non-surgical techniques, particularly autologous nanofat grafting, have shown promise in improving facial scars, with a study noting minimized scar size, improved color and texture, and absence of pain or itching after treatment.
- The combination of injectable nanofat with PRF (platelet-rich fibrin) boosts healing due to growth factors and enhances the effectiveness of the treatment through improved circulation and support of stem cells, making it a safe and effective option for scar management.
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