Isoelectric focussing in borate-poliol system is employed for measuring the blood glycosylated hemoglobin (HbA1c) levels at the treatment and prophylaxis institutions in Yalta. Examinations of normal subjects and patients with disordered glucose tolerance and apparent diabetes mellitus have revealed a significant elevation of HbA1c level in the patients with impaired glucose tolerance vs. normal subjects; these levels have been virtually the same in the diabetics and patients with impaired glucose tolerance. Over the course of health resort treatment the diabetics develop negligible changes in the HbA1c levels, paralleled by a significant reduction of glycemia on an empty stomach.

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