Pacemaker cells in the biliary system were studied by using electromyographic and histological methods. The pacemaker cells of the duodenal-biliary complex are located in the bile duct (predominantly, in its proximal part). They are characterized with enhanced spontaneous spike and slow-wave electrical activity. The pacemaker cells organize the sequential motor activity of the proximal and distal portions of ductus choledochus, with subsequent involvement of the duodenum into this activity.
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http://dx.doi.org/10.1007/s10517-014-2352-0 | DOI Listing |
J Physiol Sci
January 2025
Laboratory of Regulation in Metabolism and Behavior, Faculty of Agriculture, Kyushu University, 744 Motooka, Nishi-Ku, 819-0395, Fukuoka, Japan. Electronic address:
Intraocular pressure (IOP) plays a crucial role in glaucoma development, involving the dynamics of aqueous humor (AH). AH flows in from the ciliary body and exits through the trabecular meshwork (TM). IOP follows a circadian rhythm synchronized with the suprachiasmatic nucleus (SCN), the circadian pacemaker.
View Article and Find Full Text PDFInt J Eat Disord
January 2025
Institute of Anatomy, Rostock University Medical Center, Rostock, Germany.
Objective: Anorexia nervosa (AN) is an eating disorder characterized by severe weight loss and associated with hyperactivity and circadian rhythm disruption. However, the cellular basis of circadian rhythm disruption is poorly understood. Glial cells in the suprachiasmatic nucleus (SCN), the principal circadian pacemaker, are involved in regulating circadian rhythms.
View Article and Find Full Text PDFJ Neurophysiol
January 2025
Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington.
The persistent Na current (I) is thought to play important roles in many brain regions including the generation of inspiration in the ventral respiratory column (VRC) of mammals. The characterization of the slow inactivation of I requires long-lasting voltage steps (>1 s), which will increase intracellular Na and activate the Na/K-ATPase pump current (I). Thus, I may contribute to the previously measured slow inactivation of I and the generation of the inspiratory bursting rhythm.
View Article and Find Full Text PDFNature
January 2025
Cell and Developmental Biology Department, John Innes Centre Norwich Research Park, Norwich, UK.
Nutrient acquisition is crucial for sustaining life. Plants develop beneficial intracellular partnerships with arbuscular mycorrhiza (AM) and nitrogen-fixing bacteria to surmount the scarcity of soil nutrients and tap into atmospheric dinitrogen, respectively. Initiation of these root endosymbioses requires symbiont-induced oscillations in nuclear calcium (Ca) concentrations in root cells.
View Article and Find Full Text PDFInt Med Case Rep J
January 2025
Department of Cardiology, Heart Center, Qingdao Municipal Hospital, Qingdao, Shandong, 266071, People's Republic of China.
A case of fat liquefaction and fat particles in the pacemaker pocket observed in a female patient 12 years after implantation. The patient had no symptoms and no signs of infection or other discomfort of the heart and pacemaker pocket. The biochemical analysis showed a slight increase in cardiac troponin T, 0.
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