Purpose: We aimed to compare the radiation dose and image quality of a minimal phase window centered at 77 % compared with a wide phase window in coronary CT angiography using the second-generation 320-row CT.
Materials And Methods: Eighty patients with heart rate ≤75 bpm were retrospectively included. The first 40 patients underwent scanning with a wide phase window (65-85 %), while the last 40 patients underwent scanning with a minimal phase window centered at 77 %. Subjective image quality was graded using a 4-point scale (4 = excellent). Image noise and contrast-to-noise ratio at the proximal segments were also analyzed. The mean effective dose was derived from the dose length product multiplied by a chest conversion coefficient (κ = 0.014 mSv mGy(-1) cm(-1)).
Results: Minimal phase window scanning centered at 77 % reduced the radiation dose by 30 % compared with wide phase window scanning (1.7 vs 2.4 mSv, p = 0.0009). The subjective image quality showed no significant difference (3.75 vs 3.76, p = 0.77). No significant difference was observed in the image noise, CT number, and contrast-to-noise ratio.
Conclusions: Radiation dose could be reduced while maintaining image quality by use of a minimal phase window centered at 77 % compared with a wide phase window in coronary CT angiography using the second generation 320-row CT.
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http://dx.doi.org/10.1007/s11604-014-0321-1 | DOI Listing |
Rev Sci Instrum
January 2025
State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan 430071, China.
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State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024, China. Electronic address:
Thermochromic smart windows have been widely developed for building energy saving. However, most smart windows suffer from limited energy-saving performance, fixed phase transition temperature, and are not suitable for the temperature regulation needs of different application scenarios. Herein, a unique self-adaptive thermochromic hydrogel (HBPEC-PNA) with self-moisture-absorbing performance is reported that assembles solar energy cooling and evaporative heat dissipation.
View Article and Find Full Text PDFJ Pharm Biomed Anal
January 2025
Institute of Pharmaceutical Sciences, Pharmaceutical (Bio-)Analysis, University of Tübingen, Auf der Morgenstelle 8, Tübingen 72076, Germany. Electronic address:
Alkaptonuria (AKU) is a rare autosomal-recessive disease which is characterized through black urine and ochronosis. It is caused by deficiency of the enzyme Homogentisate 1,2-dioxygenase in the Phenylalanine/Tyrosine degradation pathway which leads to the accumulation of Homogentisic acid (HGA). Urine was provided by AKU patients and healthy controls.
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F Langhauser, Neurology, University Hospital Essen Department of Neurology, Essen, Germany.
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View Article and Find Full Text PDFJ Gen Physiol
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Institute for Neurophysiology, Uniklinik RWTH Aachen University, Aachen, Germany.
Voltage-gated sodium channels (VGSCs) in the peripheral nervous system shape action potentials (APs) and thereby support the detection of sensory stimuli. Most of the nine mammalian VGSC subtypes are expressed in nociceptors, but predominantly, three are linked to several human pain syndromes: while Nav1.7 is suggested to be a (sub-)threshold channel, Nav1.
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