Objective: To visualize the progression of endolymphatic hydrops in a patient with Ménière's disease.
Patient And Methods: A 53-year-old patient with definite Ménière's disease underwent locally enhanced inner ear magnetic resonance imaging (LEIM) for visualizing endolymphatic hydrops. Two years later, a second magnetic resonance imaging was performed for follow-up.
Results: The first magnetic resonance image confirmed the presence of endolymphatic hydrops and a treatment with betahistine was begun. Two years later, no more vertigo attacks occurred. The audiometry showed a deterioration of the hearing loss on both sides, whereas the caloric irrigation revealed normal results on both occasions. In comparison to the first examination, the second LEIM showed an augmented endolymphatic hydrops in both the cochlear and the vestibular compartments.
Conclusion: For the first time, this case of Ménière's disease shows an enlargement of endolymphatic hydrops in 1 individual in the course of 2 years. A further development of the LEIM technique is desirable to enable the volumetric quantification of endolymphatic hydrops and to monitor the effect of therapies on the course of Ménière's disease.
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http://dx.doi.org/10.1097/MAO.0000000000000393 | DOI Listing |
Laryngoscope
January 2025
Department of Otology and Skull Base Surgery, Eye, Ear, Nose, and Throat Hospital, Fudan University, Shanghai, China.
Objective: Endolymphatic sac tumors (ELSTs), as rare low-grade neoplasms, are primarily treated with surgery. This study analyzes the characteristics of tumor-infiltrating leukocytes (TILs) in ELSTs and their relationships with clinical features to explore the potential for immunotherapy in ELSTs.
Methods: Clinical data and tumor specimens of 10 ELSTs patients who underwent surgery were retrieved.
FASEB J
January 2025
Department of Otolaryngology-Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Meniere's disease (MD) is an inner ear disease characterized by endolymphatic hydrops (EH). Maintaining a regular daily routine is crucial for MD patients. However, the relationship between circadian rhythms and MD remains unclear.
View Article and Find Full Text PDFJ Clin Med
December 2024
Département d'ORL, Centre Hospitalier Universitaire de Saint Etienne, 42055 Saint-Etienne, France.
: Spontaneous nystagmus during vertigo attacks of Menière's disease has been essentially described as horizontal, beating ipsilaterally (irritative type) or contralaterally (deficit type) to the hearing loss. Our main objective was to describe the characteristics of nystagmus during vertigo attacks. The second objective was to determine the feasibility of self-video recording of eye movements by a mobile phone.
View Article and Find Full Text PDFJ Formos Med Assoc
January 2025
Department of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan; Department of Otolaryngology, Far Eastern Memorial Hospital, New Taipei, Taiwan. Electronic address:
Front Neurol
December 2024
Department of Otorhinolaryngology-Head and Neck Surgery, Tongji Medical College, Union Hospital, Huazhong University of Science and Technology, Wuhan, China.
Background: The pathological hallmark of Ménière's disease is endolymphatic hydrops, which can lead to an increase in basilar membrane stiffness and, consequently, an acceleration of the traveling wave of sound. The cochlear hydrops analysis masking procedure (CHAMP), which is an auditory brainstem response test masked at various frequencies with high-pass noise masking, uses the principle of the traveling wave velocity theory to determine the presence of endolymphatic hydrops.
Purpose: This study aimed to review the previous results of the CHAMP, expound the principles and key indicators, and discuss its clinical significance in diagnosing Ménière's disease.
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