AI Article Synopsis
- * Diagnosis involved identifying protozoa in the bone marrow and performing various tests, confirming the presence of Leishmania infantum.
- * The dog was effectively treated with amphotericin B, highlighting the need for thorough diagnostics and disease monitoring in regions where leishmaniosis is not commonly found.
Article Abstract
This case study discusses in detail for the first time the diagnosis and management of a case of leishmaniosis in a dog imported to Australia. The dog presented with epistaxis and a non-regenerative anaemia five years after being imported from Europe. Protozoa were identified within macrophages in bone marrow and splenic cytology. A Leishmania indirect fluorescent antibody test was performed and was positive while an Ehrlichia canis antibody test was negative. Polymerase chain reaction of the ITS-1 and ITS-2 regions of skin, lymph node, spleen and bone marrow were all positive for Leishmania infantum. The dog was treated with amphotericin B with a strong clinical response. The importance of thorough diagnostics in non-endemic areas, particularly Australia, is discussed. Treatment with amphotericin B is discussed. Vigilance, disease reporting and response frameworks are recommended for non-endemic areas.
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| http://dx.doi.org/10.1016/j.vetpar.2014.03.032 | DOI Listing |
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