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Pyoderma gangrenosum successfully treated with antiretroviral therapy alone in a human immunodeficiency virus-infected individual. | LitMetric

AI Article Synopsis

  • A 60-year-old man with HIV presented with painful, non-healing ulcers on his legs, leading to further investigation.
  • The biopsy revealed histological findings consistent with pyoderma gangrenosum (PG), suggesting a connection between the ulcers and his HIV condition.
  • Treatment with antiretroviral therapy alone showed significant clinical improvement, indicating it may be effective in healing PG in untreated HIV-infected individuals.

Article Abstract

We report a case of a 60-year-old man infected with human immunodeficiency virus (HIV) who was transferred to our hospital for management of multiple non-healing, painful ulcers on the lower extremities. The histological findings of the biopsy specimen were compatible with the diagnosis of pyoderma gangrenosum (PG). An association between HIV infection and the development of PG was considered after a thorough investigation. Antiretroviral therapy without the use of adjunctive immunosuppressive agents resulted in clinical improvement. Our case implies that antiretroviral therapy alone could heal PG in untreated HIV-infected patients.

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Source
http://dx.doi.org/10.1016/j.jiac.2014.03.002DOI Listing

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