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N-(5-Benzyl-sulfanyl-1,3,4-thia-diazol-2-yl)-2-(piperidin-1-yl)acetamide. | LitMetric

N-(5-Benzyl-sulfanyl-1,3,4-thia-diazol-2-yl)-2-(piperidin-1-yl)acetamide.

Acta Crystallogr Sect E Struct Rep Online

S. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of Uzbekistan, Mirzo Ulugbek Str. 77, Tashkent 100170, Uzbekistan.

Published: March 2014

The title compound, C16H20N4OS2, was synthesized by the reaction of 2-benzyl-sulfanyl-5-chloro-acetamido-1,3,4-thia-diazole and piperidine in a 1:2 ratio. The planes of the acetamide and 1,3,4-thia-diazole units are twisted by 10.8 (4)°. The thia-diazole S atom and the acetamide O atom are syn-oriented due to a hypervalent S⋯O inter-action of 2.628 (4) Å. In the crystal, mol-ecules form centrosymmetric dimers via N-H⋯N hydrogen bonds. These dimers are further connected by C-H⋯O inter-actions into (100) layers.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998473PMC
http://dx.doi.org/10.1107/S160053681400213XDOI Listing

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