Several kinds of column chromatography method were used to investigate the chemical constituents of the leaves of Lophatherum gracile. The structures of the isolated compounds were identified based on their physicochemical properties and spectral data. A new flavone C-glycoside was isolated and its structure was identified as 3'-methoxyl-luteolin 6-C-beta-D-galactopyranosiduronic acid (1 --> 2) -alpha-L-arabinopyranoside (1).
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Molecules
December 2024
UMRT INRAE 1158 BioEcoAgro, BIOlogie des Plantes et Innovation (BIOPI), Université de Picardie Jules Verne, IUT GB, Avenue des Facultés, Le Bailly, 80025 Amiens, France.
Flavonoids have been documented to have good antioxidant activities in vitro. In recent years, reports on the antioxidant activities of flavone glycosides, a subclass of flavonoids, have attracted great attention. Despite the wealth of information on this subject, the correlation between structure and function is not well understood.
View Article and Find Full Text PDFJ Chromatogr A
January 2025
Center for Mitochondria and Healthy Aging, College of Life Sciences, Yantai University, Yantai 264005, PR China. Electronic address:
In this study, a practicably complementary size exclusion chromatography and reversed-phase liquid chromatography method was constructed and applied to efficiently separate and purify structural analogs or isomers from natural products. First, a ternary styrene-divinylbenzene matrix CHP20P medium-pressure elution system was applied for Ligustrum qianluoenenst leaf crude sample pretreatment, with a recovery of 91.2 %, and 13.
View Article and Find Full Text PDFJ Agric Food Chem
December 2024
College of Horticulture, Northwest A&F University, Yangling, Shaanxi 712100, China.
Tea contains a variety of flavone -glycosides, which are important compounds that distinguish tea cultivars and tea categories. However, the biosynthesis pathway of flavone -glycosides in tea plant remains unknown, and the key enzymes involved have not been characterized. In this study, a liquid chromatography-mass spectrometry method to determine 9 flavone -glycosides was developed, and the accumulation patterns of 9 flavone -glycosides in tea plants were examined first.
View Article and Find Full Text PDFImmunopharmacol Immunotoxicol
December 2024
Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.
Isoorientin (ISO), a flavone C-glycoside, is a glycogen synthase kinase 3β (GSK3β) substrate-competitive inhibitor. ISO has potential in treatment of Alzheimer's disease (AD). An excessive activation of GSK3β can lead to neuroinflammation causing neuronal damage.
View Article and Find Full Text PDFMicrob Genom
May 2024
Research Group Intestinal Microbiology, German Institute of Human Nutrition Potsdam-Rehbruecke, 14558 Nuthetal, Germany.
The genus (family , phylum ) includes only one cultivated species so far, isolated from human faeces and capable of deglycosylating dietary polyphenols and degrading flavonoid aglycones. Another human intestinal strain not taxonomically resolved at that time was recently genome-sequenced. We analysed the genome of this novel isolate, designated , and showed its ability to deglycosylate -coupled flavone and xanthone glucosides and -coupled flavonoid glycosides.
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