Objectives: To determine the value of low-field magnetic resonance imaging in differentiating sino-nasal aspergillosis from lymphoplasmacytic rhinitis in dogs.
Methods: A retrospective study of 41 dogs (25 with lymphoplasmacytic rhinitis and 16 with sino-nasal aspergillosis) that underwent magnetic resonance imaging scan of the nasal cavity was conducted. On magnetic resonance imaging, turbinate destruction was classified as mild, moderate or severe. The cribriform plate and vomer destruction were classified as present or absent. The intensity of fluid accumulation and turbinates was classified on T1-weighted and T2-weighted images as hypointense, hyperintense and isointense based on the brightest area on the same slice.
Results: Turbinate destruction was significantly (P=0·005) associated with sino-nasal aspergillosis. On T1-weighted images, sino-nasal aspergillosis was associated with turbinate hyperintensity, while lymphoplasmacytic rhinitis was significantly (P=0·007) associated with hypointensity. On T2-weighted images, this feature was shown not to be relevant.
Clinical Significance: This study has demonstrated that turbinate destruction is the most reliable feature to differentiate sino-nasal aspergillosis from lymphoplasmacytic rhinitis and that T1-weighted image was the most useful sequence.
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http://dx.doi.org/10.1111/jsap.12223 | DOI Listing |
Med Mycol
November 2024
Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
Owing to their inherent resistance to different classes of antifungals, early identification of Fusarium spp. is crucial. In this study, 10 clinical isolates were included from patients with invasive fusariosis involving lungs, sinuses, or both.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
October 2024
Department of Otorhinolaryngology and Head and Neck Surgery, Changi General Hospital, Singapore, 2 Simei Street 3, Singapore, 529889 Singapore.
Am J Rhinol Allergy
September 2024
Department of Otolaryngology-Head and Neck Surgery, Linkou Chang Gung Memorial Hospital, Taoyuan City, Taiwan.
Med Mycol
March 2024
Division of Evolution, Infection and Genomics, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9NT, UK.
In Ghana, most laboratory diagnoses of severe mycoses are based on histopathology findings due to inadequate availability of serology, culture, and molecular tests. The aim of this study was to evaluate the spectrum of mycoses diagnosed in Ghana. We retrospectively reviewed reports from 2012 to 2021 from three major pathology laboratories in Ghana to identify reports indicating the presence of fungal elements and diagnosis of a mycosis, then extracted demographic, clinical history, site of infection, stain(s), used and diagnosed mycosis details.
View Article and Find Full Text PDFCase Summary: Feline sino-nasal aspergillosis is a rare condition with only sparse heterogeneous reports in the literature regarding its treatment. This report describes the presentation, treatment and outcome of a cat with sino-nasal aspergillosis treated by meticulous debridement in combination with topical and systemic azole therapy. Diagnosis was based on MRI, in combination with rhinoscopic assessment and visualisation of fungal plaques, followed by histopathology, fungal culture and panfungal PCR.
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