[Statistical analysis of parameters which determine yield in continuous centrifugal plateletpheresis].

Folia Haematol Int Mag Klin Morphol Blutforsch

Abteilung Transfusionsmedizin und Immunhämatologie, Universität Kiel, BRD.

Published: October 1989

In order to ensure the economical handling of thrombocyte preparations which cannot be dispensed of and provided in unlimited quantities as well as in the interest of an indulgent behaviour towards donors it is desirable to adjust the platelet content of preparations in such a way that it corresponds to a therapeutically required, but also sufficient concentration. For this purpose, it must be possible to assess the yield of an apheresis in advance. This can be made without any difficulties by applying an equation developed according to a mathematical-statistical analysis by a multiple and partial correlation from 120 cases of apheresis, which shows, however, that the yield does not depend on machine data, but in a decisive manner on the donor's initial platelet number and the separated total blood volume.

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