Fast computation of a string duplication history under no-breakpoint-reuse.

Philos Trans A Math Phys Eng Sci

Faculty of Mathematics, Physics and Informatics, Comenius University, , Mlynská dolina, 842 48 Bratislava, Slovakia.

Published: May 2014

In this paper, we provide an O(n log(2) n log log n log* n) algorithm to compute a duplication history of a string under no-breakpoint-reuse condition. The motivation of this problem stems from computational biology, in particular, from analysis of complex gene clusters. The problem is also related to computing edit distance with block operations, but, in our scenario, the start of the history is not fixed, but chosen to minimize the distance measure.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996574PMC
http://dx.doi.org/10.1098/rsta.2013.0133DOI Listing

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