[Effect of preoperative infusion volume on frequency of intraoperative nausea and vomiting as complications of spinal anaesthesia in pregnant women during caesarian operation (pilot study)].

Purpose of the study was to define a prophylactic effect of different preload volumes on the rate of intraoperative nausea and vomiting (IONV) as a complication due to spinal anaesthesia (SA) during caesarian operation (SO) in parturient. Data for analysis was collected during clinical observational multi-center research included several medical centers. Statistics involved originally developed method allowed to analyze relative risk changing along the entire interval of all applied preload volumes. The results suppose that preload is effective method of IONV prophylactics in parturient during SO under SA if only infused preload volumes do not break specially determined limits of effective interval. If preload volume value is out of this range then preinfusion may lead to increasing risk of IONV occurrence.