Sarcoidosis is a multisystem inflammatory disease characterized by the formation of noncaseating granulomas in various organs and tissues. The majority of patients with systemic sarcoidosis will present with lung and lymph node involvement. In addition, 20% have skin involvement that may be the only manifestation of the disease or may be an important prognostic marker for involvement of other organs. There are multiple forms of presentation of cutaneous sarcoidosis, which may be a true challenge.We report a patient with a one month history of an eruption of skin colored papules. Some were grouped in a symmetrical distribution on the trunk, inner arms, and lumbar region. Pathologic examination revealed an infiltrate in the papillary dermis showing a band of noncaseating granulomas along with disruption of the basal lamina and lichenoid changes. The clinicopathological correlation confirmed the diagnosis of lichenoid sarcoidosis. We consider our case interesting owing to the clinical presentation and the lichenoid distribution of granulomas.
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An Bras Dermatol
June 2024
Department of Dermatology, School of Medicine, University of Antioquia, Medellín, Colombia.
Front Med (Lausanne)
November 2023
Department of Dermatology, University of Brescia, Brescia, Italy.
Cancers (Basel)
March 2023
1st Dermatology Department, "Andreas Syggros" Hospital for Skin Diseases, National & Kapodistrian University of Athens, 16121 Athens, Greece.
Immune checkpoint blockers (ICBs) have been widely used during the last decade for the treatment of various tumors, including advanced and metastatic melanoma. While these agents have improved melanoma patients' survival rates, they have also been associated with various autoimmune toxicities, with the skin being most commonly affected. The severity of cutaneous toxicity can not only negatively affect patients' quality of life but can also limit the proper treatment of cancer.
View Article and Find Full Text PDFInt J Dermatol
June 2023
Department of Human Pathology, Tokyo Medical and Dental University, Tokyo, Japan.
Curr Probl Dermatol
June 2023
The Tattoo Clinic, Department of Dermatology, Bispebjerg University Hospital, Copenhagen, Denmark.
Cosmetic tattooing and medical tattooing of the face share basic principles and to some degree types and spectrum of technical and clinical complications known from decorative tattooing of other parts of the body. Cosmetic tattoos recently have grown exponentially in popularity in industrialized countries all over the world. The different complications and their clinical symptoms, pathophysiology, diagnosis, treatment, and prevention are analyzed versus culprit pigments and updated.
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