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Varying pixel resolution significantly improves deep learning-based carotid plaque histology segmentation.
Sci Rep
January 2025
Medical Physics, University of Wisconsin School of Medicine and Public Health (UW-SMPH), Madison, USA.
Carotid plaques-the buildup of cholesterol, calcium, cellular debris, and fibrous tissues in carotid arteries-can rupture, release microemboli into the cerebral vasculature and cause strokes. The likelihood of a plaque rupturing is thought to be associated with its composition (i.e.
View Article and Find Full Text PDFIron levels and vulnerable coronary atherosclerotic plaques.
Kardiol Pol
January 2025
Department of Coronary and Structural Heart Diseases, National Institute of Cardiology, Warszawa, Poland.
Background: Preliminary research indicates that higher iron levels are associated with worse outcomes in patients with coronary artery disease.
Aims: The study aimed to investigate the relationship between iron levels and the type and composition of coronary plaques.
Methods: In patients with ≥1 coronary stenosis ≥50% on computed tomography angiography, iron levels, presence of high-risk plaque features, such as low-attenuation plaque (LAP), napkin-ring sign, positive remodeling, and spotty calcium, as well as type and plaque composition (calcified/fibrous/fibro-fatty/necrotic core) were evaluated.
Role of Vessel Wall Magnetic Resonance Imaging in the Diagnosis of Intracranial Vasculopathies.
Cureus
November 2024
Radiodiagnosis, Sawai Man Singh (SMS) Medical College and Hospital, Jaipur, IND.
Background: Stroke is a leading cause of death and disability worldwide, affecting millions annually. Accurate etiological diagnosis is critical for the effective treatment and prevention of recurrent strokes. Traditional luminal imaging techniques like computed tomography (CT) and magnetic resonance angiography (MRA) provide limited information, focusing solely on vessel lumen characteristics.
View Article and Find Full Text PDFUltrasound Strain Imaging for Characterizing Atherosclerotic Plaque in the Carotid Arteries of Asymptomatic Subjects.
Ultrasound Med Biol
February 2025
Department of Medical Imaging, Medical UltraSound Imaging Center, Radboud University Medical Center, Nijmegen, The Netherlands; Physics of Fluids Group, University of Twente, Meander (27), Enschede, The Netherlands. Electronic address:
Objective: The rupture of vulnerable plaques in the carotid artery is a leading cause of strokes. While magnetic resonance imaging (MRI) is the standard for quantifying plaque composition, its high costs and lengthy procedure times limit large-scale use. Compound ultrasound strain imaging (CUSI) ultrasound offers a non-invasively alternative by assessing tissue deformation/strain within the arterial wall.
View Article and Find Full Text PDFHistology of pulmonary tuberculosis in a 19th-century mummy from Comiso (Sicily, Italy).
Int J Paleopathol
December 2024
Division of Paleopathology, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Italy.
Objective: The aim of this study is to investigate potential evidence of tuberculosis in mummified remains.
Materials: The natural mummy of an anonymous friar from the mortuary chapel of the church of Santa Maria della Grazia in Comiso (Sicily) METHODS: The mummy was studied through macroscopic examination; tissue sampling was conducted through breaches in the dorsal surface of the thorax. Radiological, histological and immunohistochemical analyses were performed on the pulmonary parenchyma.
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