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Dose-response analysis of infants prenatally exposed to methyl mercury: an application of a single compartment model to single-strand hair analysis. | LitMetric
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Dose-response analysis of infants prenatally exposed to methyl mercury: an application of a single compartment model to single-strand hair analysis.

C Cox T W Clarkson D O Marsh L Amin-Zaki S Tikriti G G Myers

Environ Res

Division of Biostatistics, University of Rochester School of Medicine, New York 14642.

Published: August 1989

A new method of estimating fetal exposure is used in a dose-response analysis of data from the 1971 outbreak of methyl mercury poisoning in rural Iraq. An X-ray fluorescence instrument for the measurement of single strands of human hair was employed to obtain longitudinal profiles recapitulating fetal exposure. Logit and hockey-stick models as well as nonparametric smoothing are used to describe data on delayed development and central nervous system abnormality.

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http://dx.doi.org/10.1016/s0013-9351(89)80075-1DOI Listing

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