The opisthorchiasis epidemiological situation in Ukraine and the Sumy Region that has the largest natural focus of invasion has been analyzed. Its morbidity rate is 21.6 per 100,000 population, which is more than 20 times greater than that in Ukraine. The clinical course of the disease in the endemic focus, the attribute of which is the high percentage of its latent form, has been examined. Praziquantel is the most effective drug for the etiotropic therapy of opisthorchiasis.

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