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Potential Pitfalls of IgG4 Immunohistochemical Staining on Lesional Tissue in Cutaneous Acantholytic Disorders.
Dermatopathology (Basel)
December 2024
Department of Pathology, University of Virginia, Charlottesville, VA 22903, USA.
The diagnostic utility of immunohistochemistry on paraffin-embedded sections in bullous disorders is useful when frozen tissue is not available. In pemphigus vulgaris and pemphigus foliaceus, an intercellular lace-like staining pattern of IgG4 on lesional tissue by immunohistochemistry has been described, with a comparable sensitivity and specificity to direct immunofluorescence on perilesional tissue. This study aimed to evaluate the staining pattern of IgG4 in non-immunobullous disorders to highlight the potential pitfalls when using this stain.
View Article and Find Full Text PDFBullous impetigo due to methicillin-resistant Staphylococcusaureus.
Semergen
December 2024
Department of Dermatology, Hospital Universitario y Politécnico La Fe, Valencia, Spain; Instituto de Investigación Sanitaria (IIS) La Fe, Valencia, Spain.
Common Skin Conditions in Children and Adolescents: Bacterial Infections.
FP Essent
June 2024
Department of Family and Community Medicine, University of Texas Health, San Antonio.
Article Synopsis
- * Impetigo is frequently seen in children and can be treated with topical antibiotics; however, oral antibiotics may be warranted in cases of outbreaks or multiple lesions.
- * For abscess-related issues like furuncles and carbuncles, management typically involves incision and drainage, with oral antibiotics reserved for severe cases or immunocompromised patients; methicillin-resistant coverage may be needed if treatments fail.
Extensive Non-Bullous Facial Impetigo in an Adult.
Vis J Emerg Med
July 2023
West Los Angeles Veterans Affairs Medical Center, Los Angeles, CA, USA.
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