In West Africa and Nigeria in particular, many virgin plants are still waiting to be evaluated for their medicinal importance. Claims of plants with folk medicinal applications need to be evaluated and verified. Gomphrena celosioides (family - Amaranthaceae) is a weed grown in lawns and the biological activity of the extract had earlier been established. In the present study, the plant was collected, air dried, ground and soxhlet extracted with n-hexane and two compounds were isolated from the flakes that were recovered from the n-hexane extract on cooling. Column chromatography using 5% chloroform in n-hexane effected the separation. The structures of the isolated compounds were elucidated by spectroscopic analysis using IR, NMR ((1)H and (13)C) and EI-MS. The compounds were found to be aurantiamide and aurantiamide acetate. This is the first report of isolation of these compounds in Gomphrena celosioides.
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Braz J Biol
October 2024
Universidade Federal de Mato Grosso do Sul - UFMS, Centro de Estudos em Células-Tronco, Terapia Celular e Genética Toxicológica - CeTroGen, Faculdade de Medicina, Programa de Pós-graduação em Saúde e Desenvolvimento na Região Centro-Oeste, Campo Grande, MS, Brasil.
Bioinformation
April 2022
Section of Plant Pathology and Nematology, Department of Botany, Aligarh Muslim University, Aligarh 202002, India.
Tomato plant is affected by several pathogens, including root-knot nematodes (RKNs), belonging to the genus Meloidogyne. Meloidogyne incognita is among the most potent pests infecting tomato roots. Therefore, it is of interest to discuss the management of Meloidogyne incognita using selected botanicals such as Cammelina benghalensis, Evolvulus nummularius, Gomphrena celosioides, Lindenbergia indica, Scoparia dulcis and Vernonia cinerea.
View Article and Find Full Text PDFPharmaceutics
November 2022
Department of Pharmaceutical Sciences, North Dakota State University, Fargo, ND 58102, USA.
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View Article and Find Full Text PDFRegul Toxicol Pharmacol
August 2022
Institute of Biosciences of Botucatu, Department of Structural and Functional Biology, University. Estadual Paulista - Botucatu (UNESP), São Paulo, Brazil. Electronic address:
The toxicological potential of the ethanolic extract from Gomphrena celosioides (EEGC), a medicinal plant used as a natural analgesic, was investigated in acute and subacute toxicity models in rodents. For the acute toxicity test, 2000 mg/kg of EEGC was administered orally to male and female Wistar rats, while Swiss mice received 75, 150 or 300 mg/kg of EEGC for the subacute toxicity test. Animals treated with an only dose of 2000 mg/kg EEGC showed no clinical signs of toxicity, indicating that the LD is higher than this dose.
View Article and Find Full Text PDFBMC Complement Med Ther
March 2021
Department of Botany, Faculty of Science, University of Lagos, Akoka, Lagos state, Nigeria.
Background: Plants with an ethnobotanical history are known to harbor diverse group of endophytic fungi, which constitute major natural sources of bioactive compounds. In the present study, we evaluated the antioxidant activity of endophytic fungi from eight Nigerian ethnomedicinal plants. Endophytic fungi were isolated from the leaves of Acalypha ornata, Albizia zygia, Alchornea cordifolia, Chrysophyllum albidum, Ficus exasperata, Gomphrena celosioides, Millettia thonningii, and Newbouldia laevis.
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