A promising, new, in vivo prostate dosimetry system has been developed for clinical radiation therapy. This work outlines the preliminary end-to-end testing of the accuracy and precision of the new OARtrac scintillation dosimetry system. We tested 94 calibrated plastic scintillation detector (PSD) probes before their final integration into endorectal balloon assemblies. These probes had been calibrated at The University of Texas MD Anderson Cancer Center Dosimetry Laboratory. We used a complete clinical OARtrac system including the PSD probes, charge coupled device camera monitoring system, and the manufacturer's integrated software package. The PSD probes were irradiated at 6 MV in a Solid Water® phantom. Irradiations were performed with a 6 MV linear accelerator using anterior-posterior/posterior-anterior matched fields to a maximum dose of 200 cGy in a 100 cm source-axis distance geometry. As a whole, the OARtrac system has good accuracy with a mean error of 0.01% and an error spread of ±5.4% at the 95% confidence interval. These results reflect the PSD probes' accuracy before their final insertion into endorectal balloons. Future work will test the dosimetric effects of mounting the PSD probes within the endorectal balloon assemblies.
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http://dx.doi.org/10.1088/0031-9155/59/9/N27 | DOI Listing |
ACS Nano
January 2025
Department of Physics, Indian Institute of Science, Bangalore 560012, India.
The low-frequency resistance fluctuations, or noise, in electrical resistance not only set a performance benchmark in devices but also form a sensitive tool to probe nontrivial electronic phases and band structures in solids. Here, we report the measurement of such noise in the electrical resistance in twisted bilayer graphene (tBLG), where the layers are misoriented close to the magic angle (θ ∼ 1°). At high temperatures ( ≳ 60-70 K), the power spectral density (PSD) of the fluctuation inside the low-energy moiré bands is predominantly ∝1/, where is the frequency, being generally lowest close to the magic angle, and can be well-explained within the conventional McWhorter model of the '1/ noise' with trap-assisted density-mobility fluctuations.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Center for Neuroscience, University of California, Davis, CA 95618.
How newly formed memories are preserved while brain plasticity is ongoing has been a source of debate. One idea is that synapses which experienced recent plasticity become resistant to further plasticity, a type of metaplasticity often referred to as saturation. Here, we probe the local dendritic mechanisms that limit plasticity at recently potentiated synapses.
View Article and Find Full Text PDFPLoS One
December 2024
Department of Psychology, Centre for Neuroscience in Education, University of Cambridge, Cambridge, United Kingdom.
Cortical signals have been shown to track acoustic and linguistic properties of continuous speech. This phenomenon has been measured in both children and adults, reflecting speech understanding by adults as well as cognitive functions such as attention and prediction. Furthermore, atypical low-frequency cortical tracking of speech is found in children with phonological difficulties (developmental dyslexia).
View Article and Find Full Text PDFGels
October 2024
Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, SK S7N 5C9, Canada.
An amphiphilic cellulose () hydrogel was synthesized via grafting of quaternary ammonium groups onto cellulose. The structural properties of were characterized via Fourier transform infrared (FTIR)/C solid-state NMR spectroscopy, elemental (CHN) analysis, particle size distribution (PSD), thermogravimetric analysis (TGA), and wettability was assessed through contact angle measurements. Pickering emulsions of apolar oils in water were prepared using variable weights of the hydrogel as the stabilizing agent, along with different methods of agitation (mechanical shaking and sonication).
View Article and Find Full Text PDFBioorg Chem
December 2024
Jiamusi University, Jiamusi 154007, China. Electronic address:
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