AI Article Synopsis

  • The study aimed to assess if combining oral sucrose with non-nutritive sucking can reduce pain in infants during retinopathy of prematurity screening.
  • It involved 64 infants and compared an intervention group given sucrose and a control group given sterile water before eye exams, both receiving topical anaesthetic.
  • Results showed that the sucrose group experienced significantly lower pain scores during the first eye examination, indicating potential benefits, but further research is needed to confirm effective pain relief.

Article Abstract

Aim: To evaluate the efficacy of oral sucrose combined with non-nutritive sucking for reducing pain associated with retinopathy of prematurity screening.

Methods: This was a randomised controlled study of 64 infants undergoing eye examination for retinopathy of prematurity screening. Topical anaesthetic (Proparacaine; Alcaine(®) drop 0.5%: ALCON CANADA Inc., Mississauga, Canada) was applied 30 sec before the eye examination in all infants. The infants in intervention group (Group 1, n = 32) received 0.5 mL/kg of 24% sucrose with a pacifier. The control group (Group 2, n = 32) received 0.5 mL/kg of sterile water with a pacifier.

Results: The groups had similar gestational ages (28.5 ± 2.8 weeks), mean birthweight (1304 ± 466 g) or corrected gestational age (35.4 ± 3.7 weeks) at examination. The intervention group had a significantly lower mean Premature Infant Pain Profile score during examination of the first eye, following insertion of the speculum (Group 1:13.7 ± 2.1 vs. Group 2:16.4 ± 1.8, p = 0.001).

Conclusion: Although sucrose combined with non-nutritive sucking modestly reduces pain scores during eye examinations, there is need to further studies to explore significant pain relief for infants undergoing retinopathy of prematurity screening.

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Source
http://dx.doi.org/10.1111/apa.12454DOI Listing

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